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Prognostic Role of Chronic Rhinosinusitis in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy

Background: The aim of the study was to assess the relevance of chronic rhinosinusitis (CRS) CT features to the efficacy of mechanical thrombectomy (MT) in patients with acute ischemic stroke. Methods: This study included 311 patients qualified for MT in whom the CRS features were assessed based on...

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Autores principales: Puz, Przemysław, Stryjewska-Makuch, Grażyna, Żak, Amadeusz, Rybicki, Wiktor, Student, Sebastian, Lasek-Bal, Anetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509423/
https://www.ncbi.nlm.nih.gov/pubmed/34640464
http://dx.doi.org/10.3390/jcm10194446
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author Puz, Przemysław
Stryjewska-Makuch, Grażyna
Żak, Amadeusz
Rybicki, Wiktor
Student, Sebastian
Lasek-Bal, Anetta
author_facet Puz, Przemysław
Stryjewska-Makuch, Grażyna
Żak, Amadeusz
Rybicki, Wiktor
Student, Sebastian
Lasek-Bal, Anetta
author_sort Puz, Przemysław
collection PubMed
description Background: The aim of the study was to assess the relevance of chronic rhinosinusitis (CRS) CT features to the efficacy of mechanical thrombectomy (MT) in patients with acute ischemic stroke. Methods: This study included 311 patients qualified for MT in whom the CRS features were assessed based on a CT scan, according to the Lund-Mackay (L-M) score. Clinical, inflammatory parameters, patients neurological (NIHSS) and functional status (mRS), and recanalisation efficacy (TICI) were compared between patients with mild lesions (L-M score 0–3 points)-group 1, and patients with more severe lesions (L–M score 4–24)-group 2. Results: There was a significant difference in the NIHSS on day seven after stroke onset-10 points in group 1 and 14 points in group 2, p = 0.02. NIHSS ≤ 6 points on day seven was found in 41.9% of patients in group 1, and in 27.5% in group 2, p = 0.042. There were no significant differences in mRS score and in the TICI score. L-M score, lipid abnormalities and CRP were factors associated with NIHSS ≥ 7 points on day 7. Conclusions: The CT features of CRS may be used as a prognostic tool for early prognosis assessment in stroke patients.
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spelling pubmed-85094232021-10-13 Prognostic Role of Chronic Rhinosinusitis in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy Puz, Przemysław Stryjewska-Makuch, Grażyna Żak, Amadeusz Rybicki, Wiktor Student, Sebastian Lasek-Bal, Anetta J Clin Med Article Background: The aim of the study was to assess the relevance of chronic rhinosinusitis (CRS) CT features to the efficacy of mechanical thrombectomy (MT) in patients with acute ischemic stroke. Methods: This study included 311 patients qualified for MT in whom the CRS features were assessed based on a CT scan, according to the Lund-Mackay (L-M) score. Clinical, inflammatory parameters, patients neurological (NIHSS) and functional status (mRS), and recanalisation efficacy (TICI) were compared between patients with mild lesions (L-M score 0–3 points)-group 1, and patients with more severe lesions (L–M score 4–24)-group 2. Results: There was a significant difference in the NIHSS on day seven after stroke onset-10 points in group 1 and 14 points in group 2, p = 0.02. NIHSS ≤ 6 points on day seven was found in 41.9% of patients in group 1, and in 27.5% in group 2, p = 0.042. There were no significant differences in mRS score and in the TICI score. L-M score, lipid abnormalities and CRP were factors associated with NIHSS ≥ 7 points on day 7. Conclusions: The CT features of CRS may be used as a prognostic tool for early prognosis assessment in stroke patients. MDPI 2021-09-27 /pmc/articles/PMC8509423/ /pubmed/34640464 http://dx.doi.org/10.3390/jcm10194446 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Puz, Przemysław
Stryjewska-Makuch, Grażyna
Żak, Amadeusz
Rybicki, Wiktor
Student, Sebastian
Lasek-Bal, Anetta
Prognostic Role of Chronic Rhinosinusitis in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
title Prognostic Role of Chronic Rhinosinusitis in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
title_full Prognostic Role of Chronic Rhinosinusitis in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
title_fullStr Prognostic Role of Chronic Rhinosinusitis in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
title_full_unstemmed Prognostic Role of Chronic Rhinosinusitis in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
title_short Prognostic Role of Chronic Rhinosinusitis in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
title_sort prognostic role of chronic rhinosinusitis in acute ischemic stroke patients undergoing mechanical thrombectomy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509423/
https://www.ncbi.nlm.nih.gov/pubmed/34640464
http://dx.doi.org/10.3390/jcm10194446
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