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The Impact of Morbid Obesity on the Health Outcomes of Hospital Inpatients: An Observational Study

Morbid obesity poses a significant burden on the health-care system. This study determined whether morbid obesity leads to worse health-outcomes in hospitalised patients. This retrospective-study examined nutritional data of all inpatients aged 18–79 years, with a body-mass-index (BMI) ≥ 18.5 kg/m(2...

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Autores principales: Fusco, Kellie, Thompson, Campbell, Woodman, Richard, Horwood, Chris, Hakendorf, Paul, Sharma, Yogesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509550/
https://www.ncbi.nlm.nih.gov/pubmed/34640400
http://dx.doi.org/10.3390/jcm10194382
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author Fusco, Kellie
Thompson, Campbell
Woodman, Richard
Horwood, Chris
Hakendorf, Paul
Sharma, Yogesh
author_facet Fusco, Kellie
Thompson, Campbell
Woodman, Richard
Horwood, Chris
Hakendorf, Paul
Sharma, Yogesh
author_sort Fusco, Kellie
collection PubMed
description Morbid obesity poses a significant burden on the health-care system. This study determined whether morbid obesity leads to worse health-outcomes in hospitalised patients. This retrospective-study examined nutritional data of all inpatients aged 18–79 years, with a body-mass-index (BMI) ≥ 18.5 kg/m(2) admitted over a period of 4 years at two major hospitals in Australia. Patients were divided into 3 groups for comparison: normal/overweight (BMI 18.5–29.9 kg/m(2)), obese (BMI 30–39.9 kg/m(2)) and morbidly-obese (BMI ≥ 40 kg/m(2)). Outcome measures included length-of-hospital-stay (LOS), in-hospital mortality, and 30-day readmissions. Multilevel-mixed-effects regression was used to compare clinical outcomes between the groups after adjustment for potential confounders. Of 16,579 patients, 1004 (6.1%) were classified as morbidly-obese. Morbidly-obese patients had a significantly longer median (IQR) LOS than normal/overweight patients (5 (2, 12) vs. 5 (2, 11) days, p value = 0.012) and obese-patients (5 (2, 12) vs. 5 (2, 10) days, p value = 0.036). After adjusted-analysis, morbidly-obese patients had a higher incidence of a longer LOS than normal/overweight patients (IRR 1.04; 95% CI 1.02–1.07; p value < 0.001) and obese-patients (IRR 1.13; 95% CI 1.11–1.16; p value < 0.001). Other clinical outcomes were similar between the different groups. Morbid obesity leads to a longer LOS in hospitalised patients but does not adversely affect other clinical outcomes.
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spelling pubmed-85095502021-10-13 The Impact of Morbid Obesity on the Health Outcomes of Hospital Inpatients: An Observational Study Fusco, Kellie Thompson, Campbell Woodman, Richard Horwood, Chris Hakendorf, Paul Sharma, Yogesh J Clin Med Article Morbid obesity poses a significant burden on the health-care system. This study determined whether morbid obesity leads to worse health-outcomes in hospitalised patients. This retrospective-study examined nutritional data of all inpatients aged 18–79 years, with a body-mass-index (BMI) ≥ 18.5 kg/m(2) admitted over a period of 4 years at two major hospitals in Australia. Patients were divided into 3 groups for comparison: normal/overweight (BMI 18.5–29.9 kg/m(2)), obese (BMI 30–39.9 kg/m(2)) and morbidly-obese (BMI ≥ 40 kg/m(2)). Outcome measures included length-of-hospital-stay (LOS), in-hospital mortality, and 30-day readmissions. Multilevel-mixed-effects regression was used to compare clinical outcomes between the groups after adjustment for potential confounders. Of 16,579 patients, 1004 (6.1%) were classified as morbidly-obese. Morbidly-obese patients had a significantly longer median (IQR) LOS than normal/overweight patients (5 (2, 12) vs. 5 (2, 11) days, p value = 0.012) and obese-patients (5 (2, 12) vs. 5 (2, 10) days, p value = 0.036). After adjusted-analysis, morbidly-obese patients had a higher incidence of a longer LOS than normal/overweight patients (IRR 1.04; 95% CI 1.02–1.07; p value < 0.001) and obese-patients (IRR 1.13; 95% CI 1.11–1.16; p value < 0.001). Other clinical outcomes were similar between the different groups. Morbid obesity leads to a longer LOS in hospitalised patients but does not adversely affect other clinical outcomes. MDPI 2021-09-25 /pmc/articles/PMC8509550/ /pubmed/34640400 http://dx.doi.org/10.3390/jcm10194382 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fusco, Kellie
Thompson, Campbell
Woodman, Richard
Horwood, Chris
Hakendorf, Paul
Sharma, Yogesh
The Impact of Morbid Obesity on the Health Outcomes of Hospital Inpatients: An Observational Study
title The Impact of Morbid Obesity on the Health Outcomes of Hospital Inpatients: An Observational Study
title_full The Impact of Morbid Obesity on the Health Outcomes of Hospital Inpatients: An Observational Study
title_fullStr The Impact of Morbid Obesity on the Health Outcomes of Hospital Inpatients: An Observational Study
title_full_unstemmed The Impact of Morbid Obesity on the Health Outcomes of Hospital Inpatients: An Observational Study
title_short The Impact of Morbid Obesity on the Health Outcomes of Hospital Inpatients: An Observational Study
title_sort impact of morbid obesity on the health outcomes of hospital inpatients: an observational study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509550/
https://www.ncbi.nlm.nih.gov/pubmed/34640400
http://dx.doi.org/10.3390/jcm10194382
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