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Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy

Hypertrophic cardiomyopathy (HCM) is a complex, underestimated, multifaceted disease frequently associated with left ventricular outflow tract (LVOT) obstruction. It is clearly demonstrated that this is due not only to septal hypertrophy but also to systolic anterior motion (SAM) of mitral valve lea...

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Autores principales: Affronti, Alessandro, Pruna-Guillen, Robert, Sandoval, Elena, Pereda, Daniel, Alcocer, Jorge, Castellà, Manuel, Quintana, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509570/
https://www.ncbi.nlm.nih.gov/pubmed/34640415
http://dx.doi.org/10.3390/jcm10194397
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author Affronti, Alessandro
Pruna-Guillen, Robert
Sandoval, Elena
Pereda, Daniel
Alcocer, Jorge
Castellà, Manuel
Quintana, Eduard
author_facet Affronti, Alessandro
Pruna-Guillen, Robert
Sandoval, Elena
Pereda, Daniel
Alcocer, Jorge
Castellà, Manuel
Quintana, Eduard
author_sort Affronti, Alessandro
collection PubMed
description Hypertrophic cardiomyopathy (HCM) is a complex, underestimated, multifaceted disease frequently associated with left ventricular outflow tract (LVOT) obstruction. It is clearly demonstrated that this is due not only to septal hypertrophy but also to systolic anterior motion (SAM) of mitral valve leaflets secondary to mitral valve/subvalvular apparatus abnormalities. Surgical treatment involves performing an extended septal myectomy, eventually followed by ancillary procedures to those structures responsible for maintaining LVOT obstruction, if necessary. In this review, we describe the spectrum of possible surgical techniques beyond septal myectomy and their pathophysiologic rationale.
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spelling pubmed-85095702021-10-13 Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy Affronti, Alessandro Pruna-Guillen, Robert Sandoval, Elena Pereda, Daniel Alcocer, Jorge Castellà, Manuel Quintana, Eduard J Clin Med Review Hypertrophic cardiomyopathy (HCM) is a complex, underestimated, multifaceted disease frequently associated with left ventricular outflow tract (LVOT) obstruction. It is clearly demonstrated that this is due not only to septal hypertrophy but also to systolic anterior motion (SAM) of mitral valve leaflets secondary to mitral valve/subvalvular apparatus abnormalities. Surgical treatment involves performing an extended septal myectomy, eventually followed by ancillary procedures to those structures responsible for maintaining LVOT obstruction, if necessary. In this review, we describe the spectrum of possible surgical techniques beyond septal myectomy and their pathophysiologic rationale. MDPI 2021-09-26 /pmc/articles/PMC8509570/ /pubmed/34640415 http://dx.doi.org/10.3390/jcm10194397 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Affronti, Alessandro
Pruna-Guillen, Robert
Sandoval, Elena
Pereda, Daniel
Alcocer, Jorge
Castellà, Manuel
Quintana, Eduard
Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy
title Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy
title_full Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy
title_fullStr Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy
title_full_unstemmed Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy
title_short Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy
title_sort surgery for hypertrophic obstructive cardiomyopathy: comprehensive lvot management beyond septal myectomy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509570/
https://www.ncbi.nlm.nih.gov/pubmed/34640415
http://dx.doi.org/10.3390/jcm10194397
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