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Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy
Hypertrophic cardiomyopathy (HCM) is a complex, underestimated, multifaceted disease frequently associated with left ventricular outflow tract (LVOT) obstruction. It is clearly demonstrated that this is due not only to septal hypertrophy but also to systolic anterior motion (SAM) of mitral valve lea...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509570/ https://www.ncbi.nlm.nih.gov/pubmed/34640415 http://dx.doi.org/10.3390/jcm10194397 |
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author | Affronti, Alessandro Pruna-Guillen, Robert Sandoval, Elena Pereda, Daniel Alcocer, Jorge Castellà, Manuel Quintana, Eduard |
author_facet | Affronti, Alessandro Pruna-Guillen, Robert Sandoval, Elena Pereda, Daniel Alcocer, Jorge Castellà, Manuel Quintana, Eduard |
author_sort | Affronti, Alessandro |
collection | PubMed |
description | Hypertrophic cardiomyopathy (HCM) is a complex, underestimated, multifaceted disease frequently associated with left ventricular outflow tract (LVOT) obstruction. It is clearly demonstrated that this is due not only to septal hypertrophy but also to systolic anterior motion (SAM) of mitral valve leaflets secondary to mitral valve/subvalvular apparatus abnormalities. Surgical treatment involves performing an extended septal myectomy, eventually followed by ancillary procedures to those structures responsible for maintaining LVOT obstruction, if necessary. In this review, we describe the spectrum of possible surgical techniques beyond septal myectomy and their pathophysiologic rationale. |
format | Online Article Text |
id | pubmed-8509570 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85095702021-10-13 Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy Affronti, Alessandro Pruna-Guillen, Robert Sandoval, Elena Pereda, Daniel Alcocer, Jorge Castellà, Manuel Quintana, Eduard J Clin Med Review Hypertrophic cardiomyopathy (HCM) is a complex, underestimated, multifaceted disease frequently associated with left ventricular outflow tract (LVOT) obstruction. It is clearly demonstrated that this is due not only to septal hypertrophy but also to systolic anterior motion (SAM) of mitral valve leaflets secondary to mitral valve/subvalvular apparatus abnormalities. Surgical treatment involves performing an extended septal myectomy, eventually followed by ancillary procedures to those structures responsible for maintaining LVOT obstruction, if necessary. In this review, we describe the spectrum of possible surgical techniques beyond septal myectomy and their pathophysiologic rationale. MDPI 2021-09-26 /pmc/articles/PMC8509570/ /pubmed/34640415 http://dx.doi.org/10.3390/jcm10194397 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Affronti, Alessandro Pruna-Guillen, Robert Sandoval, Elena Pereda, Daniel Alcocer, Jorge Castellà, Manuel Quintana, Eduard Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy |
title | Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy |
title_full | Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy |
title_fullStr | Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy |
title_full_unstemmed | Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy |
title_short | Surgery for Hypertrophic Obstructive Cardiomyopathy: Comprehensive LVOT Management beyond Septal Myectomy |
title_sort | surgery for hypertrophic obstructive cardiomyopathy: comprehensive lvot management beyond septal myectomy |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509570/ https://www.ncbi.nlm.nih.gov/pubmed/34640415 http://dx.doi.org/10.3390/jcm10194397 |
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