Cargando…

Integrating Statistical and Machine-Learning Approach for Meta-Analysis of Bisphenol A-Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival

Bisphenols are important environmental pollutants that are extensively studied due to different detrimental effects, while the molecular mechanisms behind these effects are less well understood. Like other environmental pollutants, bisphenols are being tested in various experimental models, creating...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lukashina, Nina, Williams, Michael J., Kartysheva, Elena, Virko, Elizaveta, Kudłak, Błażej, Fredriksson, Robert, Spjuth, Ola, Schiöth, Helgi B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509605/ https://www.ncbi.nlm.nih.gov/pubmed/34639124 http://dx.doi.org/10.3390/ijms221910785

Ejemplares similares

SimVec: predicting polypharmacy side effects for new drugs
por: Lukashina, Nina, et al.
Publicado: (2022)

Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures
por: Kudłak, Błażej, et al.
Publicado: (2022)

Stabilities of bisphenol A diglycidyl ether, bisphenol F diglycidyl ether, and their derivatives under controlled conditions analyzed using liquid chromatography coupled with tandem mass spectrometry
por: Szczepańska, Natalia, et al.
Publicado: (2019)

Binary Mixtures of Selected Bisphenols in the Environment: Their Toxicity in Relationship to Individual Constituents
por: Owczarek, Katarzyna, et al.
Publicado: (2018)

Role of the Synergistic Interactions of Environmental Pollutants in the Development of Cancer
por: Lagunas‐Rangel, Francisco Alejandro, et al.
Publicado: (2022)

Exposure to the environmental pollutant bisphenol A diglycidyl ether (BADGE) causes cell over-proliferation in Drosophila
por: Williams, Michael J., et al.
Publicado: (2020)

Novel applications of Machine Learning in cheminformatics
por: Spjuth, Ola
Publicado: (2018)

The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors
por: Nordström, Karl JV, et al.
Publicado: (2008)

The G protein-coupled receptor subset of the rat genome
por: Gloriam, David E, et al.
Publicado: (2007)

Multivariate Statistical Approach for Nephrines in Women with Obesity
por: Robeva, Ralitsa, et al.
Publicado: (2021)

Synergy conformal prediction applied to large-scale bioactivity datasets and in federated learning
por: Norinder, Ulf, et al.
Publicado: (2021)

The Dispanins: A Novel Gene Family of Ancient Origin That Contains 14 Human Members
por: Sällman Almén, Markus, et al.
Publicado: (2012)

The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi
por: Krishnan, Arunkumar, et al.
Publicado: (2012)

Insights into the Origin of Nematode Chemosensory GPCRs: Putative Orthologs of the Srw Family Are Found across Several Phyla of Protostomes
por: Krishnan, Arunkumar, et al.
Publicado: (2014)

Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin
por: Almén, Markus Sällman, et al.
Publicado: (2009)

The Solute Carrier Families Have a Remarkably Long Evolutionary History with the Majority of the Human Families Present before Divergence of Bilaterian Species
por: Höglund, Pär J., et al.
Publicado: (2011)

Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4
por: Lagunas-Rangel, Francisco Alejandro, et al.
Publicado: (2023)

Assessment of toxic and endocrine potential of substances migrating from selected toys and baby products
por: Szczepańska, Natalia, et al.
Publicado: (2016)

Impact of selected drugs and their binary mixtures on the germination of Sorghum bicolor (sorgo) seeds
por: Wieczerzak, Monika, et al.
Publicado: (2018)

Towards interoperable and reproducible QSAR analyses: Exchange of datasets
por: Spjuth, Ola, et al.
Publicado: (2010)

Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae
por: Västermark, Åke, et al.
Publicado: (2011)

The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents
por: Haitina, Tatjana, et al.
Publicado: (2009)

Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns
por: Lekholm, Emilia, et al.
Publicado: (2021)

The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals
por: Krishnan, Arunkumar, et al.
Publicado: (2014)

Advances in Predictions of Oral Bioavailability of Candidate Drugs in Man with New Machine Learning Methodology
por: Fagerholm, Urban, et al.
Publicado: (2021)

The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924
por: Jacobsson, Josefin A, et al.
Publicado: (2009)

Altered cerebellar–insular–parietal–cingular subnetwork in adolescents in the earliest stages of anorexia nervosa: a network–based statistic analysis
por: Gaudio, Santino, et al.
Publicado: (2018)

Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression
por: Sreedharan, Smitha, et al.
Publicado: (2010)

Identification of Distant Agouti-Like Sequences and Re-Evaluation of the Evolutionary History of the Agouti-Related Peptide (AgRP)
por: Västermark, Åke, et al.
Publicado: (2012)

Machine Learning Strategies When Transitioning between Biological Assays
por: Arvidsson McShane, Staffan, et al.
Publicado: (2021)

Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat
por: Haitina, Tatjana, et al.
Publicado: (2008)

The G Protein–Coupled Receptor Subset of the Chicken Genome
por: Lagerström, Malin C, et al.
Publicado: (2006)

Chemometric Assessment and Best-Fit Function Modelling of the Toxic Potential of Selected Food Packaging Extracts
por: Kudłak, Błażej, et al.
Publicado: (2018)

Influence of Storage Time and Temperature on the Toxicity, Endocrine Potential, and Migration of Epoxy Resin Precursors in Extracts of Food Packaging Materials
por: Kudłak, Błażej, et al.
Publicado: (2019)

SPRIT: Identifying horizontal gene transfer in rooted phylogenetic trees
por: Hill, Tobias, et al.
Publicado: (2010)

The STK33-Linked SNP rs4929949 Is Associated with Obesity and BMI in Two Independent Cohorts of Swedish and Greek Children
por: Rask-Andersen, Mathias, et al.
Publicado: (2013)

CDKAL1-Related Single Nucleotide Polymorphisms Are Associated with Insulin Resistance in a Cross-Sectional Cohort of Greek Children
por: Rask-Andersen, Mathias, et al.
Publicado: (2014)

BDNF Polymorphisms Are Linked to Poorer Working Memory Performance, Reduced Cerebellar and Hippocampal Volumes and Differences in Prefrontal Cortex in a Swedish Elderly Population
por: Brooks, Samantha J., et al.
Publicado: (2014)

BioImg.org: A Catalog of Virtual Machine Images for the Life Sciences
por: Dahlö, Martin, et al.
Publicado: (2015)

Large-scale ligand-based predictive modelling using support vector machines
por: Alvarsson, Jonathan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1cpsf7i6asbomvnrosl0mtggjc