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Residual Helicity at the Active Site of the Histidine Phosphocarrier, HPr, Modulates Binding Affinity to Its Natural Partners

The phosphoenolpyruvate-dependent phosphotransferase system (PTS) modulates the preferential use of sugars in bacteria. The first proteins in the cascade are common to all organisms (EI and HPr). The active site of HPr involves a histidine (His15) located immediately before the beginning of the firs...

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Detalles Bibliográficos
Autores principales: Neira, José L., Ortega-Alarcón, David, Rizzuti, Bruno, Palomino-Schätzlein, Martina, Velázquez-Campoy, Adrián, Falcó, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509676/
https://www.ncbi.nlm.nih.gov/pubmed/34639146
http://dx.doi.org/10.3390/ijms221910805