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Residual Helicity at the Active Site of the Histidine Phosphocarrier, HPr, Modulates Binding Affinity to Its Natural Partners
The phosphoenolpyruvate-dependent phosphotransferase system (PTS) modulates the preferential use of sugars in bacteria. The first proteins in the cascade are common to all organisms (EI and HPr). The active site of HPr involves a histidine (His15) located immediately before the beginning of the firs...
Autores principales: | Neira, José L., Ortega-Alarcón, David, Rizzuti, Bruno, Palomino-Schätzlein, Martina, Velázquez-Campoy, Adrián, Falcó, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509676/ https://www.ncbi.nlm.nih.gov/pubmed/34639146 http://dx.doi.org/10.3390/ijms221910805 |
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