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Effect of Structural Changes Induced by Deletion of (54)FLRAPSWF(61) Sequence in αB-crystallin on Chaperone Function and Anti-Apoptotic Activity

Previously, we showed that the removal of the 54–61 residues from αB-crystallin (αBΔ54–61) results in a fifty percent reduction in the oligomeric mass and a ten-fold increase in chaperone-like activity. In this study, we investigated the oligomeric organization changes in the deletion mutant contrib...

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Detalles Bibliográficos
Autores principales: Mahalingam, Sundararajan, Karmakar, Srabani, Santhoshkumar, Puttur, Sharma, Krishna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509813/
https://www.ncbi.nlm.nih.gov/pubmed/34639110
http://dx.doi.org/10.3390/ijms221910771