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Effect of Structural Changes Induced by Deletion of (54)FLRAPSWF(61) Sequence in αB-crystallin on Chaperone Function and Anti-Apoptotic Activity
Previously, we showed that the removal of the 54–61 residues from αB-crystallin (αBΔ54–61) results in a fifty percent reduction in the oligomeric mass and a ten-fold increase in chaperone-like activity. In this study, we investigated the oligomeric organization changes in the deletion mutant contrib...
Autores principales: | Mahalingam, Sundararajan, Karmakar, Srabani, Santhoshkumar, Puttur, Sharma, Krishna K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509813/ https://www.ncbi.nlm.nih.gov/pubmed/34639110 http://dx.doi.org/10.3390/ijms221910771 |
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