Cargando…
Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review
The wide application of magnesium alloys as biodegradable implant materials is limited because of their fast degradation rate. Hydroxyapatite (HA) coating can reduce the degradation rate of Mg alloys and improve the biological activity of Mg alloys, and has the ability of bone induction and bone con...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509838/ https://www.ncbi.nlm.nih.gov/pubmed/34639949 http://dx.doi.org/10.3390/ma14195550 |
_version_ | 1784582441155952640 |
---|---|
author | Chen, Junxiu Yang, Yang Etim, Iniobong P. Tan, Lili Yang, Ke Misra, R. D. K. Wang, Jianhua Su, Xuping |
author_facet | Chen, Junxiu Yang, Yang Etim, Iniobong P. Tan, Lili Yang, Ke Misra, R. D. K. Wang, Jianhua Su, Xuping |
author_sort | Chen, Junxiu |
collection | PubMed |
description | The wide application of magnesium alloys as biodegradable implant materials is limited because of their fast degradation rate. Hydroxyapatite (HA) coating can reduce the degradation rate of Mg alloys and improve the biological activity of Mg alloys, and has the ability of bone induction and bone conduction. The preparation of HA coating on the surface of degradable Mg alloys can improve the existing problems, to a certain extent. This paper reviewed different preparation methods of HA coatings on biodegradable Mg alloys, and their effects on magnesium alloys’ degradation, biocompatibility, and osteogenic properties. However, no coating prepared can meet the above requirements. There was a lack of systematic research on the degradation of coating samples in vivo, and the osteogenic performance. Therefore, future research can focus on combining existing coating preparation technology and complementary advantages to develop new coating preparation techniques, to obtain more balanced coatings. Second, further study on the metabolic mechanism of HA-coated Mg alloys in vivo can help to predict its degradation behavior, and finally achieve controllable degradation, and further promote the study of the osteogenic effect of HA-coated Mg alloys in vivo. |
format | Online Article Text |
id | pubmed-8509838 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85098382021-10-13 Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review Chen, Junxiu Yang, Yang Etim, Iniobong P. Tan, Lili Yang, Ke Misra, R. D. K. Wang, Jianhua Su, Xuping Materials (Basel) Review The wide application of magnesium alloys as biodegradable implant materials is limited because of their fast degradation rate. Hydroxyapatite (HA) coating can reduce the degradation rate of Mg alloys and improve the biological activity of Mg alloys, and has the ability of bone induction and bone conduction. The preparation of HA coating on the surface of degradable Mg alloys can improve the existing problems, to a certain extent. This paper reviewed different preparation methods of HA coatings on biodegradable Mg alloys, and their effects on magnesium alloys’ degradation, biocompatibility, and osteogenic properties. However, no coating prepared can meet the above requirements. There was a lack of systematic research on the degradation of coating samples in vivo, and the osteogenic performance. Therefore, future research can focus on combining existing coating preparation technology and complementary advantages to develop new coating preparation techniques, to obtain more balanced coatings. Second, further study on the metabolic mechanism of HA-coated Mg alloys in vivo can help to predict its degradation behavior, and finally achieve controllable degradation, and further promote the study of the osteogenic effect of HA-coated Mg alloys in vivo. MDPI 2021-09-24 /pmc/articles/PMC8509838/ /pubmed/34639949 http://dx.doi.org/10.3390/ma14195550 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Chen, Junxiu Yang, Yang Etim, Iniobong P. Tan, Lili Yang, Ke Misra, R. D. K. Wang, Jianhua Su, Xuping Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review |
title | Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review |
title_full | Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review |
title_fullStr | Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review |
title_full_unstemmed | Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review |
title_short | Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review |
title_sort | recent advances on development of hydroxyapatite coating on biodegradable magnesium alloys: a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509838/ https://www.ncbi.nlm.nih.gov/pubmed/34639949 http://dx.doi.org/10.3390/ma14195550 |
work_keys_str_mv | AT chenjunxiu recentadvancesondevelopmentofhydroxyapatitecoatingonbiodegradablemagnesiumalloysareview AT yangyang recentadvancesondevelopmentofhydroxyapatitecoatingonbiodegradablemagnesiumalloysareview AT etiminiobongp recentadvancesondevelopmentofhydroxyapatitecoatingonbiodegradablemagnesiumalloysareview AT tanlili recentadvancesondevelopmentofhydroxyapatitecoatingonbiodegradablemagnesiumalloysareview AT yangke recentadvancesondevelopmentofhydroxyapatitecoatingonbiodegradablemagnesiumalloysareview AT misrardk recentadvancesondevelopmentofhydroxyapatitecoatingonbiodegradablemagnesiumalloysareview AT wangjianhua recentadvancesondevelopmentofhydroxyapatitecoatingonbiodegradablemagnesiumalloysareview AT suxuping recentadvancesondevelopmentofhydroxyapatitecoatingonbiodegradablemagnesiumalloysareview |