T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy

HIV cerebrospinal fluid (CSF) escape, where HIV is suppressed in blood but detectable in CSF, occurs when HIV persists in the CNS despite antiretroviral therapy (ART). To determine the virus producing cell type and whether lowered CSF ART levels are responsible for CSF escape, we collected blood and...

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Detalles Bibliográficos
Autores principales: Lustig, Gila, Cele, Sandile, Karim, Farina, Derache, Anne, Ngoepe, Abigail, Khan, Khadija, Gosnell, Bernadett I., Moosa, Mahomed-Yunus S., Ntshuba, Ntombi, Marais, Suzaan, Jeena, Prakash M., Govender, Katya, Adamson, John, Kløverpris, Henrik, Gupta, Ravindra K., Harrichandparsad, Rohen, Patel, Vinod B., Sigal, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509856/
https://www.ncbi.nlm.nih.gov/pubmed/34555123
http://dx.doi.org/10.1371/journal.ppat.1009871

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