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Predicting PY motif-mediated protein-protein interactions in the Nedd4 family of ubiquitin ligases

The Nedd4 family contains several structurally related but functionally distinct HECT-type ubiquitin ligases. The members of the Nedd4 family are known to recognize substrates through their multiple WW domains, which recognize PY motifs (PPxY, LPxY) or phospho-threonine or phospho-serine residues. T...

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Detalles Bibliográficos
Autores principales: Hatstat, A. Katherine, Pupi, Michael D., McCafferty, Dewey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509885/
https://www.ncbi.nlm.nih.gov/pubmed/34637467
http://dx.doi.org/10.1371/journal.pone.0258315

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