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Heterodimer-heterotetramer formation mediates enhanced sensor activity in a biophysical model for BMP signaling

Numerous stages of organismal development rely on the cellular interpretation of gradients of secreted morphogens including members of the Bone Morphogenetic Protein (BMP) family through transmembrane receptors. Early gradients of BMPs drive dorsal/ventral patterning throughout the animal kingdom in...

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Detalles Bibliográficos
Autores principales:	Karim, Md. Shahriar, Madamanchi, Aasakiran, Dutko, James A., Mullins, Mary C., Umulis, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509922/ https://www.ncbi.nlm.nih.gov/pubmed/34591841 http://dx.doi.org/10.1371/journal.pcbi.1009422

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