Design, Synthesis, Biological Evaluation and In Silico Study of Benzyloxybenzaldehyde Derivatives as Selective ALDH1A3 Inhibitors

Aldehyde dehydrogenase 1A3 (ALDH1A3) has recently gained attention from researchers in the cancer field. Several studies have reported ALDH1A3 overexpression in different cancer types, which has been found to correlate with poor treatment recovery. Therefore, finding selective inhibitors against ALD...

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Detalles Bibliográficos
Autores principales: Ibrahim, Ali I. M., Ikhmais, Balqis, Batlle, Elisabet, AbuHarb, Waed K., Jha, Vibhu, Jaradat, Khaled T., Jiménez, Rafael, Pequerul, Raquel, Parés, Xavier, Farrés, Jaume, Pors, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510124/
https://www.ncbi.nlm.nih.gov/pubmed/34641313
http://dx.doi.org/10.3390/molecules26195770

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