Regioselective C-H Functionalization of the Six-Membered Ring of the 6,5-Fused Heterocyclic Systems: An Overview

The regioselective C-H functionalization of the five-membered ring of the 6,5-fused heterocyclic systems is nowadays well documented due to its high reactivity compared to the six-membered ring. So, developing new procedures of C-H functionalization of the six-membered ring “by thinking out of the b...

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Autores principales: Faarasse, Soukaina, El Brahmi, Nabil, Guillaumet, Gérald, El Kazzouli, Saïd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510187/
https://www.ncbi.nlm.nih.gov/pubmed/34641306
http://dx.doi.org/10.3390/molecules26195763
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author Faarasse, Soukaina
El Brahmi, Nabil
Guillaumet, Gérald
El Kazzouli, Saïd
author_facet Faarasse, Soukaina
El Brahmi, Nabil
Guillaumet, Gérald
El Kazzouli, Saïd
author_sort Faarasse, Soukaina
collection PubMed
description The regioselective C-H functionalization of the five-membered ring of the 6,5-fused heterocyclic systems is nowadays well documented due to its high reactivity compared to the six-membered ring. So, developing new procedures of C-H functionalization of the six-membered ring “by thinking out of the box” is extremely challenging, which explains the limited number of reports published to date. This review paper aims to highlight advances achieved in this emerging chemistry research and discusses recently reported methods.
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spelling pubmed-85101872021-10-13 Regioselective C-H Functionalization of the Six-Membered Ring of the 6,5-Fused Heterocyclic Systems: An Overview Faarasse, Soukaina El Brahmi, Nabil Guillaumet, Gérald El Kazzouli, Saïd Molecules Review The regioselective C-H functionalization of the five-membered ring of the 6,5-fused heterocyclic systems is nowadays well documented due to its high reactivity compared to the six-membered ring. So, developing new procedures of C-H functionalization of the six-membered ring “by thinking out of the box” is extremely challenging, which explains the limited number of reports published to date. This review paper aims to highlight advances achieved in this emerging chemistry research and discusses recently reported methods. MDPI 2021-09-23 /pmc/articles/PMC8510187/ /pubmed/34641306 http://dx.doi.org/10.3390/molecules26195763 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Faarasse, Soukaina
El Brahmi, Nabil
Guillaumet, Gérald
El Kazzouli, Saïd
Regioselective C-H Functionalization of the Six-Membered Ring of the 6,5-Fused Heterocyclic Systems: An Overview
title Regioselective C-H Functionalization of the Six-Membered Ring of the 6,5-Fused Heterocyclic Systems: An Overview
title_full Regioselective C-H Functionalization of the Six-Membered Ring of the 6,5-Fused Heterocyclic Systems: An Overview
title_fullStr Regioselective C-H Functionalization of the Six-Membered Ring of the 6,5-Fused Heterocyclic Systems: An Overview
title_full_unstemmed Regioselective C-H Functionalization of the Six-Membered Ring of the 6,5-Fused Heterocyclic Systems: An Overview
title_short Regioselective C-H Functionalization of the Six-Membered Ring of the 6,5-Fused Heterocyclic Systems: An Overview
title_sort regioselective c-h functionalization of the six-membered ring of the 6,5-fused heterocyclic systems: an overview
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510187/
https://www.ncbi.nlm.nih.gov/pubmed/34641306
http://dx.doi.org/10.3390/molecules26195763
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