Common Shortcomings in Study on Radiopharmaceutical Design Research: A Case Study of (99m)Tc-Labelled Methotrexate

The aim of the work carried out was to draw attention to shortcomings that often appear at the stage of designing new radiopharmaceuticals. Based on a case study of (99m)Tc-labelled methotrexate, this article describes frequent mistakes or misconceptions present not only in the referenced studies, b...

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Detalles Bibliográficos
Autores principales: Koźmiński, Przemysław, Halik, Paweł Krzysztof, Chesori, Raphael, Gniazdowska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510358/
https://www.ncbi.nlm.nih.gov/pubmed/34641406
http://dx.doi.org/10.3390/molecules26195862
Descripción
Sumario:The aim of the work carried out was to draw attention to shortcomings that often appear at the stage of designing new radiopharmaceuticals. Based on a case study of (99m)Tc-labelled methotrexate, this article describes frequent mistakes or misconceptions present not only in the referenced studies, but also in numerous radiopharmaceutical studies. The recommendations provided in this article highlight fundamental aspects of the credibility of radiopharmaceutical scientific research leading to the reliable results.

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