Two-Component Nanoparticle Vaccine Displaying Glycosylated Spike S1 Domain Induces Neutralizing Antibody Response against SARS-CoV-2 Variants

Vaccines pave the way out of the SARS-CoV-2 pandemic. Besides mRNA and adenoviral vector vaccines, effective protein-based vaccines are needed for immunization against current and emerging variants. We have developed a virus-like particle (VLP)-based vaccine using the baculovirus-insect cell express...

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Detalles Bibliográficos
Autores principales: van Oosten, Linda, Altenburg, Jort J., Fougeroux, Cyrielle, Geertsema, Corinne, van den End, Fred, Evers, Wendy A. C., Westphal, Adrie H., Lindhoud, Simon, van den Berg, Willy, Swarts, Daan C., Deurhof, Laurens, Suhrbier, Andreas, Le, Thuy T., Torres Morales, Shessy, Myeni, Sebenzile K., Kikkert, Marjolein, Sander, Adam F., de Jongh, Willem Adriaan, Dagil, Robert, Nielsen, Morten A., Salanti, Ali, Søgaard, Max, Keijzer, Timo M. P., Weijers, Dolf, Eppink, Michel H. M., Wijffels, René H., van Oers, Monique M., Martens, Dirk E., Pijlman, Gorben P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510518/
https://www.ncbi.nlm.nih.gov/pubmed/34634927
http://dx.doi.org/10.1128/mBio.01813-21

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