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Human Monoclonal Antibodies against NS1 Protein Protect against Lethal West Nile Virus Infection

Envelope protein-targeted vaccines for flaviviruses are limited by concerns of antibody-dependent enhancement (ADE) of infections. Nonstructural protein 1 (NS1) provides an alternative vaccine target that avoids this risk since this protein is absent from the virion. Beyond its intracellular role in...

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Detalles Bibliográficos
Autores principales:	Wessel, Alex W., Doyle, Michael P., Engdahl, Taylor B., Rodriguez, Jessica, Crowe, James E., Diamond, Michael S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510529/ https://www.ncbi.nlm.nih.gov/pubmed/34634945 http://dx.doi.org/10.1128/mBio.02440-21

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