A Vimentin-Targeting Oral Compound with Host-Directed Antiviral and Anti-Inflammatory Actions Addresses Multiple Features of COVID-19 and Related Diseases

Damage in COVID-19 results from both the SARS-CoV-2 virus and its triggered overactive host immune responses. Therapeutic agents that focus solely on reducing viral load or hyperinflammation fail to provide satisfying outcomes in all cases. Although viral and cellular factors have been extensively p...

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Detalles Bibliográficos
Autores principales: Li, Zhizhen, Wu, Jianping, Zhou, Ji, Yuan, Baoshi, Chen, Jiqiao, Wu, Wanchen, Mo, Lian, Qu, Zhipeng, Zhou, Fei, Dong, Yingying, Huang, Kai, Liu, Zhiwei, Wang, Tao, Symmes, Deebie, Gu, Jingliang, Sho, Eiketsu, Zhang, Jingping, Chen, Ruihuan, Xu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510534/
https://www.ncbi.nlm.nih.gov/pubmed/34634931
http://dx.doi.org/10.1128/mBio.02542-21

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