DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli

Encounters between DNA replication and transcription can cause genomic disruption, particularly when the two meet head-on. Whether these conflicts produce point mutations is debated. This paper presents detailed analyses of a large collection of mutations generated during mutation accumulation exper...

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Detalles Bibliográficos
Autores principales: Foster, Patricia L., Niccum, Brittany A., Lee, Heewook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510543/
https://www.ncbi.nlm.nih.gov/pubmed/34634932
http://dx.doi.org/10.1128/mBio.02503-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510543/
https://www.ncbi.nlm.nih.gov/pubmed/34634932
http://dx.doi.org/10.1128/mBio.02503-21

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