Evaluation of adverse events and health‐related quality of life in patients with colorectal cancer receiving ambulatory home‐based chemotherapy in Thailand

AIMS: To compare adverse events and health‐related quality of life in ambulatory home‐based chemotherapy with those in inpatient. DESIGN: Prospective non‐randomized observational study. METHODS: Participants were divided into two groups according to patients’ preference receiving chemotherapy. RESUL...

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Detalles Bibliográficos
Autores principales: Sirilerttrakul, Suwannee, Wannakansophon, Noppaskan, Utthiya, Pinyo, Ckumdee, Sineenuch, Tangteerakoon, Patamaporn, Chansriwong, Phichai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510724/
https://www.ncbi.nlm.nih.gov/pubmed/34382364
http://dx.doi.org/10.1002/nop2.1016
Descripción
Sumario:AIMS: To compare adverse events and health‐related quality of life in ambulatory home‐based chemotherapy with those in inpatient. DESIGN: Prospective non‐randomized observational study. METHODS: Participants were divided into two groups according to patients’ preference receiving chemotherapy. RESULTS: Sixty‐four participants were enrolled in the inpatient, and 111 were in an ambulatory home‐based chemotherapy. The frequency of anaemia, neutropenia and thrombocytopenia was significantly higher in inpatient group than in ambulatory home‐based chemotherapy group (p < .001, <.001 and .002, respectively). Nausea, mucositis, and fatigue were more common in ambulatory home‐based chemotherapy group than in inpatient group (p < .001, .022, and .005, respectively). Patients in the ambulatory home‐based chemotherapy group showed higher social well‐being (SWB) scores than inpatient group (coefficient 1.92, 95% confidence interval [CI] 0.65 to 3.19, p .003).

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