Cargando…

Randomized multicenter noninferiority phase III clinical trial of the first biosimilar of eculizumab

Currently, eculizumab is the main effective treatment for paroxysmal nocturnal hemoglobinuria (PNH). The aim of this randomized multicenter noninferiority study was to evaluate the efficacy and safety of the Biosimilar (Elizaria) in comparison with the Originator (Soliris) in patients with PNH. Bios...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kulagin, Alexander D., Ptushkin, Vadim V., Lukina, Elena A., Davydkin, Igor L., Korobkin, Alexander V., Shamrai, Vladimir S., Konstantinova, Tatyana S., Kaporskaya, Tatyana S., Mitina, Tatyana A., Ksenzova, Tatyana I., Zuev, Evgeny V., Markova, Oksana A., Gapchenko, Elena V., Kudlay, Dmitry A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510904/ https://www.ncbi.nlm.nih.gov/pubmed/34398258 http://dx.doi.org/10.1007/s00277-021-04624-7

Ejemplares similares

Serum Uric Acid Predicts Declining of Circulating Proangiogenic Mononuclear Progenitor Cells in Chronic Heart Failure Patients
por: Berezin, Alexander E., et al.
Publicado: (2014)

The predictive role of circulating microparticles in patients with chronic heart failure()
por: Berezin, Alexander E., et al.
Publicado: (2014)

The Association of Subclinical Hypothyroidism and Pattern of Circulating Endothelial-Derived Microparticles Among Chronic Heart Failure Patients
por: Berezin, Alexander E., et al.
Publicado: (2015)

The utility of biomarker risk prediction score in patients with chronic heart failure
por: Berezin, Alexander E., et al.
Publicado: (2016)

The Mechanisms of the Regulation of Immune Response in Patients with Comorbidity of Chronic Obstructive Pulmonary Disease and Asthma
por: Kalinina, Elena P., et al.
Publicado: (2016)

Ibrutinib in combination with rituximab is highly effective in treatment of chronic lymphocytic leukemia patients with steroid refractory and relapsed autoimmune cytopenias
por: Nikitin, Eugene, et al.
Publicado: (2023)

Comparison of biosimilar Tigerase and Pulmozyme in long-term symptomatic therapy of patients with cystic fibrosis and severe pulmonary impairment (subgroup analysis of a Phase III randomized open-label clinical trial (NCT04468100))
por: Amelina, Elena L., et al.
Publicado: (2021)

Laccases with Variable Properties from Different Strains of Steccherinum ochraceum: Does Glycosylation Matter?
por: Glazunova, Olga A., et al.
Publicado: (2019)

Composition of fatty acids in plasma and erythrocytes and eicosanoids level in patients with metabolic syndrome
por: Novgorodtseva, Tatyana P, et al.
Publicado: (2011)

The real value of words: how target language linguistic modelling of foreign language teaching content shapes students’ professional identity
por: Bagiyan, Alexander Y., et al.
Publicado: (2021)

The first data on the innervation of the lophophore in the rhynchonelliform brachiopod Hemithiris psittacea: what is the ground pattern of the lophophore in lophophorates?
por: Temereva, Elena N., et al.
Publicado: (2017)

The nervous system of the most complex lophophore provides new insights into the evolution of Brachiopoda
por: Temereva, Elena N., et al.
Publicado: (2021)

Pattern of endothelial progenitor cells and apoptotic endothelial cell-derived microparticles in chronic heart failure patients with preserved and reduced left ventricular ejection fraction
por: Berezin, Alexander E., et al.
Publicado: (2016)

Data regarding association between serum osteoprotegerin level, numerous of circulating endothelial-derived and mononuclear-derived progenitor cells in patients with metabolic syndrome
por: Berezin, Alexander E., et al.
Publicado: (2016)

Altruism and Phenoptosis as Programs Supported by Evolution
por: Shilovsky, Gregory A., et al.
Publicado: (2021)

Clinical and Genetic Characteristics of COL2A1-Associated Skeletal Dysplasias in 60 Russian Patients: Part I
por: Markova, Tatyana, et al.
Publicado: (2022)

Does the c.-14C>T Mutation in the IFITM5 Gene Provide Identical Phenotypes for Osteogenesis Imperfecta Type V? Data from Russia and a Literature Review
por: Tyurin, Anton, et al.
Publicado: (2022)

Biosimilar erythropoietin in anemia treatment (BEAT)—Efficacy and safety of a 1:1 dose conversion from EPREX(®) to EPIAO(®) in patients with end-stage renal disease on hemodialysis: A prospective, randomized, double blind, parallel group study
por: Miao, Bolong, et al.
Publicado: (2022)

PB2051: POPULATION PHARMACOKINETIC/PHARMACODYNAMIC/EFFICACY MODELING OF SB12 (PROPOSED ECULIZUMAB BIOSIMILAR) AND REFERENCE ECULIZUMAB
por: Lee, Hyuna, et al.
Publicado: (2023)

Lipid-Induced Mechanisms of Metabolic Syndrome
por: Denisenko, Yulia K., et al.
Publicado: (2020)

Role of iron, zinc and reduced glutathione in oxidative stress induction by low pH in rat brain synaptosomes
por: Pekun, Tatyana G, et al.
Publicado: (2014)

Acoustic Structure and Contextual Use of Calls by Captive Male and Female Cheetahs (Acinonyx jubatus)
por: Smirnova, Darya S., et al.
Publicado: (2016)

A Randomized Controlled Trial to Assess the Impact of Proper Insulin Injection Technique Training on Glycemic Control
por: Misnikova, Inna V., et al.
Publicado: (2017)

Mitochondrial Electron Transport Chain in Heavy Metal-Induced Neurotoxicity: Effects of Cadmium, Mercury, and Copper
por: Belyaeva, Elena A., et al.
Publicado: (2012)

The γ-Core Motif Peptides of Plant AMPs as Novel Antimicrobials for Medicine and Agriculture
por: Slezina, Marina P., et al.
Publicado: (2022)

PB2683: MODERN DIAGNOSTIC CAPABILITIES OF THE OPHTHALMOLOGICAL STATUS OF PATIENTS WITH ONCO-HEMATOLOGICAL DISEASES.
por: Yusef, Yusef N, et al.
Publicado: (2023)

Modification of fatty acids composition in erythrocytes lipids in arterial hypertension associated with dyslipidemia
por: Novgorodtseva, Tatyana P, et al.
Publicado: (2011)

Two Separate Cases: Complex Chromosomal Abnormality Involving Three Chromosomes and Small Supernumerary Marker Chromosome in Patients with Impaired Reproductive Function
por: Karamysheva, Tatyana V., et al.
Publicado: (2020)

The γ-Core Motif Peptides of AMPs from Grasses Display Inhibitory Activity against Human and Plant Pathogens
por: Slezina, Marina P., et al.
Publicado: (2022)

Long-term data on the proposed adalimumab biosimilar BCD-057 in patients with moderate to severe psoriasis: A randomized controlled trial
por: Samtsov, Alexey V., et al.
Publicado: (2022)

Cathepsin G—Not Only Inflammation: The Immune Protease Can Regulate Normal Physiological Processes
por: Zamolodchikova, Tatyana S., et al.
Publicado: (2020)

Coral Lipidome: Molecular Species of Phospholipids, Glycolipids, Betaine Lipids, and Sphingophosphonolipids
por: Sikorskaya, Tatyana V.
Publicado: (2023)

PB1853: OUTCOMES REFRACTORY/RELAPSED ACUTE MYELOID LEUKEMIA WITH EXTRAMEDULLARY MANIFESTATIONS AFTER GEMTUZUMAB OZOGAMICIN THERAPY
por: Ayubova, Bella, et al.
Publicado: (2023)

Pattern of circulating microparticles in chronic heart failure patients with metabolic syndrome: Relevance to neurohumoral and inflammatory activation
por: Berezin, Alexander E., et al.
Publicado: (2015)

Immunomorphologic Manifestations in Mice Liver Infected with Influenza A/H5N1, A/Goose/Krasnoozerskoye/627/05 Strain
por: Potapova, Oxana V., et al.
Publicado: (2013)

Agaricus bisporus Crude Extract: Characterization and Analytical Application
por: Morosanova, Maria A., et al.
Publicado: (2020)

Modification of the fatty acid composition of the erythrocyte membrane in patients with chronic respiratory diseases
por: Novgorodtseva, Tatyana P, et al.
Publicado: (2013)

Chemical Diversity of Soft Coral Steroids and Their Pharmacological Activities
por: Ermolenko, Ekaterina V., et al.
Publicado: (2020)

Identification of a Novel de Novo Variant in the SYT2 Gene Causing a Rare Type of Distal Hereditary Motor Neuropathy
por: Mironovich, Olga, et al.
Publicado: (2020)

A Crosstalk between the Biorhythms and Gatekeepers of Longevity: Dual Role of Glycogen Synthase Kinase-3
por: Shilovsky, Gregory A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1p5m721d8cvurl7t7f5g3q1m8p