Cargando…

Efficacy of Body Armor in Protection Against Blast Injuries Using a Swine Model in a Confined Space with a Blast Tube

The purpose of this study was to clarify whether or not body armor would protect the body of a swine model using a blast tube built at National Defense Medical College, which is the first such blast tube in Japan. Seventeen pigs were divided into two groups: the body armor group and the non-body arm...

Descripción completa

Detalles Bibliográficos
Autores principales: Sekine, Yasumasa, Saitoh, Daizoh, Yoshimura, Yuya, Fujita, Masanori, Araki, Yoshiyuki, Kobayashi, Yasushi, Kusumi, Hitomi, Yamagishi, Satomi, Suto, Yuki, Tamaki, Hiroshi, Ono, Yosuke, Mizukaki, Toshiharu, Nemoto, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510944/
https://www.ncbi.nlm.nih.gov/pubmed/33686618
http://dx.doi.org/10.1007/s10439-021-02750-x
_version_ 1784582681640566784
author Sekine, Yasumasa
Saitoh, Daizoh
Yoshimura, Yuya
Fujita, Masanori
Araki, Yoshiyuki
Kobayashi, Yasushi
Kusumi, Hitomi
Yamagishi, Satomi
Suto, Yuki
Tamaki, Hiroshi
Ono, Yosuke
Mizukaki, Toshiharu
Nemoto, Manabu
author_facet Sekine, Yasumasa
Saitoh, Daizoh
Yoshimura, Yuya
Fujita, Masanori
Araki, Yoshiyuki
Kobayashi, Yasushi
Kusumi, Hitomi
Yamagishi, Satomi
Suto, Yuki
Tamaki, Hiroshi
Ono, Yosuke
Mizukaki, Toshiharu
Nemoto, Manabu
author_sort Sekine, Yasumasa
collection PubMed
description The purpose of this study was to clarify whether or not body armor would protect the body of a swine model using a blast tube built at National Defense Medical College, which is the first such blast tube in Japan. Seventeen pigs were divided into two groups: the body armor group and the non-body armor group. Under intravenous anesthesia, the pigs were tightly fixed in the left lateral position on a table and exposed from the back neck to the upper lumbar back to the blast wave and wind with or without body armor, with the driving pressure of the blast tube set to 3.0 MPa. When the surviving and dead pigs were compared, blood gas analyses revealed significant differences in PaO2, PaCO2, and pH in the super-early phase. All pigs injured by the blast wave and wind had lung hemorrhage. All 6 animals in the body armor group and 6 of the 11 animals in the control group survived for 3 hours after injury. Respiratory arrest immediately after exposure to the blast wave was considered to influence the mortality in our pig model. Body armor may have a beneficial effect in protecting against respiratory arrest immediately after an explosion.
format Online
Article
Text
id pubmed-8510944
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Springer International Publishing
record_format MEDLINE/PubMed
spelling pubmed-85109442021-10-27 Efficacy of Body Armor in Protection Against Blast Injuries Using a Swine Model in a Confined Space with a Blast Tube Sekine, Yasumasa Saitoh, Daizoh Yoshimura, Yuya Fujita, Masanori Araki, Yoshiyuki Kobayashi, Yasushi Kusumi, Hitomi Yamagishi, Satomi Suto, Yuki Tamaki, Hiroshi Ono, Yosuke Mizukaki, Toshiharu Nemoto, Manabu Ann Biomed Eng Original Article The purpose of this study was to clarify whether or not body armor would protect the body of a swine model using a blast tube built at National Defense Medical College, which is the first such blast tube in Japan. Seventeen pigs were divided into two groups: the body armor group and the non-body armor group. Under intravenous anesthesia, the pigs were tightly fixed in the left lateral position on a table and exposed from the back neck to the upper lumbar back to the blast wave and wind with or without body armor, with the driving pressure of the blast tube set to 3.0 MPa. When the surviving and dead pigs were compared, blood gas analyses revealed significant differences in PaO2, PaCO2, and pH in the super-early phase. All pigs injured by the blast wave and wind had lung hemorrhage. All 6 animals in the body armor group and 6 of the 11 animals in the control group survived for 3 hours after injury. Respiratory arrest immediately after exposure to the blast wave was considered to influence the mortality in our pig model. Body armor may have a beneficial effect in protecting against respiratory arrest immediately after an explosion. Springer International Publishing 2021-03-08 2021 /pmc/articles/PMC8510944/ /pubmed/33686618 http://dx.doi.org/10.1007/s10439-021-02750-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Sekine, Yasumasa
Saitoh, Daizoh
Yoshimura, Yuya
Fujita, Masanori
Araki, Yoshiyuki
Kobayashi, Yasushi
Kusumi, Hitomi
Yamagishi, Satomi
Suto, Yuki
Tamaki, Hiroshi
Ono, Yosuke
Mizukaki, Toshiharu
Nemoto, Manabu
Efficacy of Body Armor in Protection Against Blast Injuries Using a Swine Model in a Confined Space with a Blast Tube
title Efficacy of Body Armor in Protection Against Blast Injuries Using a Swine Model in a Confined Space with a Blast Tube
title_full Efficacy of Body Armor in Protection Against Blast Injuries Using a Swine Model in a Confined Space with a Blast Tube
title_fullStr Efficacy of Body Armor in Protection Against Blast Injuries Using a Swine Model in a Confined Space with a Blast Tube
title_full_unstemmed Efficacy of Body Armor in Protection Against Blast Injuries Using a Swine Model in a Confined Space with a Blast Tube
title_short Efficacy of Body Armor in Protection Against Blast Injuries Using a Swine Model in a Confined Space with a Blast Tube
title_sort efficacy of body armor in protection against blast injuries using a swine model in a confined space with a blast tube
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510944/
https://www.ncbi.nlm.nih.gov/pubmed/33686618
http://dx.doi.org/10.1007/s10439-021-02750-x
work_keys_str_mv AT sekineyasumasa efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube
AT saitohdaizoh efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube
AT yoshimurayuya efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube
AT fujitamasanori efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube
AT arakiyoshiyuki efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube
AT kobayashiyasushi efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube
AT kusumihitomi efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube
AT yamagishisatomi efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube
AT sutoyuki efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube
AT tamakihiroshi efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube
AT onoyosuke efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube
AT mizukakitoshiharu efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube
AT nemotomanabu efficacyofbodyarmorinprotectionagainstblastinjuriesusingaswinemodelinaconfinedspacewithablasttube