Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

Leptomeningeal disease (LMD) is a devastating complication of solid tumor malignancies, with dire prognosis and no effective systemic treatment options. Over the past decade, the incidence of LMD has steadily increased due to therapeutics that have extended the survival of cancer patients, highlight...

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Detalles Bibliográficos
Autores principales: Prakadan, Sanjay M., Alvarez-Breckenridge, Christopher A., Markson, Samuel C., Kim, Albert E., Klein, Robert H., Nayyar, Naema, Navia, Andrew W., Kuter, Benjamin M., Kolb, Kellie E., Bihun, Ivanna, Mora, Joana L., Bertalan, Mia Solana, Shaw, Brian, White, Michael, Kaplan, Alexander, Stocking, Jackson H., Wadsworth, Marc H., Lee, Eudocia Q., Chukwueke, Ugonma, Wang, Nancy, Subramanian, Megha, Rotem, Denisse, Cahill, Daniel P., Adalsteinsson, Viktor A., Miller, Jeffrey W., Sullivan, Ryan J., Carter, Scott L., Brastianos, Priscilla K., Shalek, Alex K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511044/
https://www.ncbi.nlm.nih.gov/pubmed/34642316
http://dx.doi.org/10.1038/s41467-021-25860-5

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