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Preclinical development of a Pfs230-Pfs48/45 chimeric malaria transmission-blocking vaccine

The Plasmodium falciparum Pfs230 and Pfs48/45 proteins are leading candidates for a malaria transmission-blocking vaccine (TBV). Previously, we showed that a Pfs230–Pfs48/45 fusion protein elicits higher levels of functional antibodies than the individual antigens, but low yields hampered progressio...

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Detalles Bibliográficos
Autores principales:	Singh, Susheel K., Plieskatt, Jordan, Chourasia, Bishwanath K., Singh, Vandana, Bengtsson, Karin Lövgren, Reimer, Jenny M., van Daalen, Renate C., Teelen, Karina, van de Vegte-Bolmer, Marga, van Gemert, Geert-Jan, Jore, Matthijs M., Theisen, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511065/ https://www.ncbi.nlm.nih.gov/pubmed/34642303 http://dx.doi.org/10.1038/s41541-021-00383-8

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