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Joint single-cell multiomic analysis in Wnt3a induced asymmetric stem cell division

Wnt signaling usually functions through a spatial gradient. Localized Wnt3a signaling can induce the asymmetric division of mouse embryonic stem cells, where proximal daughter cells maintain self-renewal and distal daughter cells acquire hallmarks of differentiation. Here, we develop an approach, sa...

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Detalles Bibliográficos
Autores principales: Sun, Zhongxing, Tang, Yin, Zhang, Yanjun, Fang, Yuan, Jia, Junqi, Zeng, Weiwu, Fang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511096/
https://www.ncbi.nlm.nih.gov/pubmed/34642323
http://dx.doi.org/10.1038/s41467-021-26203-0