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Joint single-cell multiomic analysis in Wnt3a induced asymmetric stem cell division
Wnt signaling usually functions through a spatial gradient. Localized Wnt3a signaling can induce the asymmetric division of mouse embryonic stem cells, where proximal daughter cells maintain self-renewal and distal daughter cells acquire hallmarks of differentiation. Here, we develop an approach, sa...
Autores principales: | Sun, Zhongxing, Tang, Yin, Zhang, Yanjun, Fang, Yuan, Jia, Junqi, Zeng, Weiwu, Fang, Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511096/ https://www.ncbi.nlm.nih.gov/pubmed/34642323 http://dx.doi.org/10.1038/s41467-021-26203-0 |
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