SIRT2-mediated deacetylation and deubiquitination of C/EBPβ prevents ethanol-induced liver injury

Protein acetylation has emerged to play pivotal roles in alcoholic liver disease (ALD). Sirutin 2 (SIRT2) is a nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylase involved in the regulation of aging, metabolism, and stress. However, the role of SIRT2 in ALD remains unclear. Here, we rep...

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Detalles Bibliográficos
Autores principales: Zhang, Yingting, Long, Xidai, Ruan, Xin, Wei, Qian, Zhang, Lin, Wo, Lulu, Huang, Dongdong, Lin, Longshuai, Wang, Difei, Xia, Li, Zhao, Qinghua, Liu, Junling, Zhao, Qian, He, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511299/
https://www.ncbi.nlm.nih.gov/pubmed/34642310
http://dx.doi.org/10.1038/s41421-021-00326-6

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