Lysophosphatidic Acid–Induced EGFR Transactivation Promotes Gastric Cancer Cell DNA Replication by Stabilizing Geminin in the S Phase

Geminin, an inhibitor of the DNA replication licensing factor, chromatin licensing and DNA replication factor (Cdt) 1, is essential for the maintenance of genomic integrity. As a multifunctional protein, geminin is also involved in tumor progression, but the molecular details are largely unknown. He...

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Detalles Bibliográficos
Autores principales: Zhao, Haile, Gezi, Gezi, Tian, Xiaoxia, Jia, Peijun, Morigen, Morigen, Fan, Lifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511314/
https://www.ncbi.nlm.nih.gov/pubmed/34658851
http://dx.doi.org/10.3389/fphar.2021.706240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511314/
https://www.ncbi.nlm.nih.gov/pubmed/34658851
http://dx.doi.org/10.3389/fphar.2021.706240

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