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Lysophosphatidic Acid–Induced EGFR Transactivation Promotes Gastric Cancer Cell DNA Replication by Stabilizing Geminin in the S Phase

Geminin, an inhibitor of the DNA replication licensing factor, chromatin licensing and DNA replication factor (Cdt) 1, is essential for the maintenance of genomic integrity. As a multifunctional protein, geminin is also involved in tumor progression, but the molecular details are largely unknown. He...

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Detalles Bibliográficos
Autores principales:	Zhao, Haile, Gezi, Gezi, Tian, Xiaoxia, Jia, Peijun, Morigen, Morigen, Fan, Lifei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511314/ https://www.ncbi.nlm.nih.gov/pubmed/34658851 http://dx.doi.org/10.3389/fphar.2021.706240

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