Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size

OBJECTIVE: Recent studies have found aristaless-related homeobox gene (ARX)/pancreatic and duodenal homeobox 1 (PDX1), alpha-thalassemia/mental retardation X-linked (ATRX)/death domain-associated protein (DAXX) and alternative lengthening of telomeres (ALT) to be promising prognostic biomarkers for...

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Detalles Bibliográficos
Autores principales: Hackeng, Wenzel M, Brosens, Lodewijk A A, Kim, Joo Young, O'Sullivan, Roderick, Sung, You-Na, Liu, Ta-Chiang, Cao, Dengfeng, Heayn, Michelle, Brosnan-Cashman, Jacqueline, An, Soyeon, Morsink, Folkert H M, Heidsma, Charlotte M, Valk, Gerlof D, Vriens, Menno R, Nieveen van Dijkum, Els, Offerhaus, G Johan A, Dreijerink, Koen M A, Zeh, Herbert, Zureikat, Amer H, Hogg, Melissa, Lee, Kenneth, Geller, David, Marsh, J Wallis, Paniccia, Alessandro, Ongchin, Melanie, Pingpank, James F, Bahary, Nathan, Aijazi, Muaz, Brand, Randall, Chennat, Jennifer, Das, Rohit, Fasanella, Kenneth E, Khalid, Asif, McGrath, Kevin, Sarkaria, Savreet, Singh, Harkirat, Slivka, Adam, Nalesnik, Michael, Han, Xiaoli, Nikiforova, Marina N, Lawlor, Rita Teresa, Mafficini, Andrea, Rusev, Boris, Corbo, Vincenzo, Luchini, Claudio, Bersani, Samantha, Pea, Antonio, Cingarlini, Sara, Landoni, Luca, Salvia, Roberto, Milione, Massimo, Milella, Michele, Scarpa, Aldo, Hong, Seung-Mo, Heaphy, Christopher M, Singhi, Aatur D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Pancreas
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511349/
https://www.ncbi.nlm.nih.gov/pubmed/33849943
http://dx.doi.org/10.1136/gutjnl-2020-322595

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