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Sanguisorbae Radix Suppresses Colorectal Tumor Growth Through PD-1/PD-L1 Blockade and Synergistic Effect With Pembrolizumab in a Humanized PD-L1-Expressing Colorectal Cancer Mouse Model

Immune checkpoints such as programmed death-1 (PD-1) have been proven as antitumor targets by enhancing cytotoxic T cell activity. All immune checkpoint blockades are antibody therapeutics that have large size and high affinity, as well as known immune-related side effects and low responses. To over...

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Detalles Bibliográficos
Autores principales:	Lee, Eun-Ji, Kim, Ji Hye, Kim, Tae In, Kim, Yeon-Ji, Pak, Malk Eun, Jeon, Chang Hyun, Park, Yeo Jin, Li, Wei, Kim, Young Soo, Choi, Jang-Gi, Chung, Hwan-Suck
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511399/ https://www.ncbi.nlm.nih.gov/pubmed/34659228 http://dx.doi.org/10.3389/fimmu.2021.737076

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