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Betaine Attenuates Osteoarthritis by Inhibiting Osteoclastogenesis and Angiogenesis in Subchondral Bone

Osteoarthritis (OA) is the most common type of arthritis with no effective therapy. Subchondral bone and overlying articular cartilage are closely associated and function as “osteo-chondral unit” in the joint. Abnormal mechanical load leads to activated osteoclast activity and increased bone resorpt...

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Detalles Bibliográficos
Autores principales: Yajun, Wang, Jin, Cui, Zhengrong, Gu, Chao, Fang, Yan, Hu, Weizong, Weng, Xiaoqun, Li, Qirong, Zhou, Huiwen, Chen, Hao, Zhang, Jiawei, Guo, Xinchen, Zhuang, Shihao, Sheng, Sicheng, Wang, Xiao, Chen, Jiacan, Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511433/
https://www.ncbi.nlm.nih.gov/pubmed/34658862
http://dx.doi.org/10.3389/fphar.2021.723988