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Betaine Attenuates Osteoarthritis by Inhibiting Osteoclastogenesis and Angiogenesis in Subchondral Bone
Osteoarthritis (OA) is the most common type of arthritis with no effective therapy. Subchondral bone and overlying articular cartilage are closely associated and function as “osteo-chondral unit” in the joint. Abnormal mechanical load leads to activated osteoclast activity and increased bone resorpt...
Autores principales: | Yajun, Wang, Jin, Cui, Zhengrong, Gu, Chao, Fang, Yan, Hu, Weizong, Weng, Xiaoqun, Li, Qirong, Zhou, Huiwen, Chen, Hao, Zhang, Jiawei, Guo, Xinchen, Zhuang, Shihao, Sheng, Sicheng, Wang, Xiao, Chen, Jiacan, Su |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511433/ https://www.ncbi.nlm.nih.gov/pubmed/34658862 http://dx.doi.org/10.3389/fphar.2021.723988 |
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