A Cyclic Peptide Epitope of an Under-Explored VEGF-B Loop 1 Demonstrated In Vivo Anti-Angiogenic and Anti-Tumor Activities

Pathological angiogenesis is mainly initiated by the binding of abnormal expressed vascular endothelial growth factors (VEGFs) to their receptors (VEGFRs). Blocking the VEGF/VEGFR interaction is a clinically proven treatment in cancer. Our previous work by epitope scan had identified cyclic peptides...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Xu, Meng, Hu, Haofeng, Zhang, Lun, Ye, Fei, Jin, Jia, Fang, Hongming, Chen, Jian, Chen, Guiqian, Broussy, Sylvain, Vidal, Michel, Lv, Zhengbing, Liu, Wang-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511632/
https://www.ncbi.nlm.nih.gov/pubmed/34658874
http://dx.doi.org/10.3389/fphar.2021.734544

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