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Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis

Primary CNS vasculitis is an inflammatory brain disease commonly misdiagnosed affecting the medium and small vessels of the CNS. Due to its broad and non-specific clinical and radiological manifestations; Its diagnosis remains challenging. New diagnostic tools and biomarkers which increase specifici...

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Autores principales: Abouzied, Moheieldin, AlSalloum, Riyadh, AlHarbi, Omar, Suhaibani, Mohanned Al, AlMuhaideb, Ahmad, Sugair, Abdulaziz Al, Qahtani, Mohammed Al
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511689/
https://www.ncbi.nlm.nih.gov/pubmed/34691342
http://dx.doi.org/10.1016/j.radcr.2021.09.017
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author Abouzied, Moheieldin
AlSalloum, Riyadh
AlHarbi, Omar
Suhaibani, Mohanned Al
AlMuhaideb, Ahmad
Sugair, Abdulaziz Al
Qahtani, Mohammed Al
author_facet Abouzied, Moheieldin
AlSalloum, Riyadh
AlHarbi, Omar
Suhaibani, Mohanned Al
AlMuhaideb, Ahmad
Sugair, Abdulaziz Al
Qahtani, Mohammed Al
author_sort Abouzied, Moheieldin
collection PubMed
description Primary CNS vasculitis is an inflammatory brain disease commonly misdiagnosed affecting the medium and small vessels of the CNS. Due to its broad and non-specific clinical and radiological manifestations; Its diagnosis remains challenging. New diagnostic tools and biomarkers which increase specificity and facilitate the diagnosis for patients with suspected vasculitis are highly desirable to enable physicians to start therapy that can alter its potential aggressive course like immunosuppressant. This case report highlights the potential role of (18)F-choline PET/MRI as a novel imaging tool that might help in the right clinical scenario in the diagnosis of this disease. Furthermore, it speculates on its secondary role in monitoring the response to immunosuppressant therapy.
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spelling pubmed-85116892021-10-21 Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis Abouzied, Moheieldin AlSalloum, Riyadh AlHarbi, Omar Suhaibani, Mohanned Al AlMuhaideb, Ahmad Sugair, Abdulaziz Al Qahtani, Mohammed Al Radiol Case Rep Case Report Primary CNS vasculitis is an inflammatory brain disease commonly misdiagnosed affecting the medium and small vessels of the CNS. Due to its broad and non-specific clinical and radiological manifestations; Its diagnosis remains challenging. New diagnostic tools and biomarkers which increase specificity and facilitate the diagnosis for patients with suspected vasculitis are highly desirable to enable physicians to start therapy that can alter its potential aggressive course like immunosuppressant. This case report highlights the potential role of (18)F-choline PET/MRI as a novel imaging tool that might help in the right clinical scenario in the diagnosis of this disease. Furthermore, it speculates on its secondary role in monitoring the response to immunosuppressant therapy. Elsevier 2021-10-06 /pmc/articles/PMC8511689/ /pubmed/34691342 http://dx.doi.org/10.1016/j.radcr.2021.09.017 Text en © 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Abouzied, Moheieldin
AlSalloum, Riyadh
AlHarbi, Omar
Suhaibani, Mohanned Al
AlMuhaideb, Ahmad
Sugair, Abdulaziz Al
Qahtani, Mohammed Al
Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis
title Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis
title_full Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis
title_fullStr Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis
title_full_unstemmed Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis
title_short Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis
title_sort fused (18)f-choline pet/mri: a potential non-invasive biomarker imaging tool in cerebral vasculitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511689/
https://www.ncbi.nlm.nih.gov/pubmed/34691342
http://dx.doi.org/10.1016/j.radcr.2021.09.017
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