Cargando…
Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis
Primary CNS vasculitis is an inflammatory brain disease commonly misdiagnosed affecting the medium and small vessels of the CNS. Due to its broad and non-specific clinical and radiological manifestations; Its diagnosis remains challenging. New diagnostic tools and biomarkers which increase specifici...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511689/ https://www.ncbi.nlm.nih.gov/pubmed/34691342 http://dx.doi.org/10.1016/j.radcr.2021.09.017 |
_version_ | 1784582820243439616 |
---|---|
author | Abouzied, Moheieldin AlSalloum, Riyadh AlHarbi, Omar Suhaibani, Mohanned Al AlMuhaideb, Ahmad Sugair, Abdulaziz Al Qahtani, Mohammed Al |
author_facet | Abouzied, Moheieldin AlSalloum, Riyadh AlHarbi, Omar Suhaibani, Mohanned Al AlMuhaideb, Ahmad Sugair, Abdulaziz Al Qahtani, Mohammed Al |
author_sort | Abouzied, Moheieldin |
collection | PubMed |
description | Primary CNS vasculitis is an inflammatory brain disease commonly misdiagnosed affecting the medium and small vessels of the CNS. Due to its broad and non-specific clinical and radiological manifestations; Its diagnosis remains challenging. New diagnostic tools and biomarkers which increase specificity and facilitate the diagnosis for patients with suspected vasculitis are highly desirable to enable physicians to start therapy that can alter its potential aggressive course like immunosuppressant. This case report highlights the potential role of (18)F-choline PET/MRI as a novel imaging tool that might help in the right clinical scenario in the diagnosis of this disease. Furthermore, it speculates on its secondary role in monitoring the response to immunosuppressant therapy. |
format | Online Article Text |
id | pubmed-8511689 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-85116892021-10-21 Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis Abouzied, Moheieldin AlSalloum, Riyadh AlHarbi, Omar Suhaibani, Mohanned Al AlMuhaideb, Ahmad Sugair, Abdulaziz Al Qahtani, Mohammed Al Radiol Case Rep Case Report Primary CNS vasculitis is an inflammatory brain disease commonly misdiagnosed affecting the medium and small vessels of the CNS. Due to its broad and non-specific clinical and radiological manifestations; Its diagnosis remains challenging. New diagnostic tools and biomarkers which increase specificity and facilitate the diagnosis for patients with suspected vasculitis are highly desirable to enable physicians to start therapy that can alter its potential aggressive course like immunosuppressant. This case report highlights the potential role of (18)F-choline PET/MRI as a novel imaging tool that might help in the right clinical scenario in the diagnosis of this disease. Furthermore, it speculates on its secondary role in monitoring the response to immunosuppressant therapy. Elsevier 2021-10-06 /pmc/articles/PMC8511689/ /pubmed/34691342 http://dx.doi.org/10.1016/j.radcr.2021.09.017 Text en © 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Abouzied, Moheieldin AlSalloum, Riyadh AlHarbi, Omar Suhaibani, Mohanned Al AlMuhaideb, Ahmad Sugair, Abdulaziz Al Qahtani, Mohammed Al Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis |
title | Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis |
title_full | Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis |
title_fullStr | Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis |
title_full_unstemmed | Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis |
title_short | Fused (18)F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis |
title_sort | fused (18)f-choline pet/mri: a potential non-invasive biomarker imaging tool in cerebral vasculitis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511689/ https://www.ncbi.nlm.nih.gov/pubmed/34691342 http://dx.doi.org/10.1016/j.radcr.2021.09.017 |
work_keys_str_mv | AT abouziedmoheieldin fused18fcholinepetmriapotentialnoninvasivebiomarkerimagingtoolincerebralvasculitis AT alsalloumriyadh fused18fcholinepetmriapotentialnoninvasivebiomarkerimagingtoolincerebralvasculitis AT alharbiomar fused18fcholinepetmriapotentialnoninvasivebiomarkerimagingtoolincerebralvasculitis AT suhaibanimohannedal fused18fcholinepetmriapotentialnoninvasivebiomarkerimagingtoolincerebralvasculitis AT almuhaidebahmad fused18fcholinepetmriapotentialnoninvasivebiomarkerimagingtoolincerebralvasculitis AT sugairabdulazizal fused18fcholinepetmriapotentialnoninvasivebiomarkerimagingtoolincerebralvasculitis AT qahtanimohammedal fused18fcholinepetmriapotentialnoninvasivebiomarkerimagingtoolincerebralvasculitis |