Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021

We evaluated routine testing with SARS-CoV-2 Delta variant-specific RT-PCR in regional hospital laboratories in addition to centralised national genomic surveillance in the Netherlands during June and July 2021. The increase of the Delta variant detected by RT-PCR correlated well with data from geno...

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Autores principales: Molenkamp, Richard, Fanoy, Ewout, Derickx, Leonie, de Groot, Theun, Jonges, Marcel, Leenstra, Tjalling, Nijhuis, Roel, Pas, Suzan, Vahidnia, Ali, von Wintersdorff, Christian, Mulder, Bert, Koopmans, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2021
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511753/
https://www.ncbi.nlm.nih.gov/pubmed/34622759
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.40.2100921
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author Molenkamp, Richard
Fanoy, Ewout
Derickx, Leonie
de Groot, Theun
Jonges, Marcel
Leenstra, Tjalling
Nijhuis, Roel
Pas, Suzan
Vahidnia, Ali
von Wintersdorff, Christian
Mulder, Bert
Koopmans, Marion
author_facet Molenkamp, Richard
Fanoy, Ewout
Derickx, Leonie
de Groot, Theun
Jonges, Marcel
Leenstra, Tjalling
Nijhuis, Roel
Pas, Suzan
Vahidnia, Ali
von Wintersdorff, Christian
Mulder, Bert
Koopmans, Marion
author_sort Molenkamp, Richard
collection PubMed
description We evaluated routine testing with SARS-CoV-2 Delta variant-specific RT-PCR in regional hospital laboratories in addition to centralised national genomic surveillance in the Netherlands during June and July 2021. The increase of the Delta variant detected by RT-PCR correlated well with data from genomic surveillance and was available ca 2 weeks earlier. This rapid identification of the relative abundance and increase of SARS-CoV-2 variants of concern may have important benefits for implementation of local public health measures.
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spelling pubmed-85117532021-11-02 Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021 Molenkamp, Richard Fanoy, Ewout Derickx, Leonie de Groot, Theun Jonges, Marcel Leenstra, Tjalling Nijhuis, Roel Pas, Suzan Vahidnia, Ali von Wintersdorff, Christian Mulder, Bert Koopmans, Marion Euro Surveill Rapid Communication We evaluated routine testing with SARS-CoV-2 Delta variant-specific RT-PCR in regional hospital laboratories in addition to centralised national genomic surveillance in the Netherlands during June and July 2021. The increase of the Delta variant detected by RT-PCR correlated well with data from genomic surveillance and was available ca 2 weeks earlier. This rapid identification of the relative abundance and increase of SARS-CoV-2 variants of concern may have important benefits for implementation of local public health measures. European Centre for Disease Prevention and Control (ECDC) 2021-10-07 /pmc/articles/PMC8511753/ /pubmed/34622759 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.40.2100921 Text en This article is copyright of the authors or their affiliated institutions, 2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Molenkamp, Richard
Fanoy, Ewout
Derickx, Leonie
de Groot, Theun
Jonges, Marcel
Leenstra, Tjalling
Nijhuis, Roel
Pas, Suzan
Vahidnia, Ali
von Wintersdorff, Christian
Mulder, Bert
Koopmans, Marion
Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021
title Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021
title_full Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021
title_fullStr Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021
title_full_unstemmed Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021
title_short Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021
title_sort supplementing sars-cov-2 genomic surveillance with pcr-based variant detection for real-time actionable information, the netherlands, june to july 2021
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511753/
https://www.ncbi.nlm.nih.gov/pubmed/34622759
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.40.2100921
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