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Interferon-λ Improves the Efficacy of Intranasally or Rectally Administered Influenza Subunit Vaccines by a Thymic Stromal Lymphopoietin-Dependent Mechanism

Previous work showed that interferon-λ (IFN-λ) can trigger the synthesis of thymic stromal lymphopoietin (TSLP) by specialized epithelial cells in the upper airways of mice, thereby improving the performance of intranasally administered influenza vaccines. Here we demonstrate that protein-only influ...

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Detalles Bibliográficos
Autores principales:	Ye, Liang, Schnepf, Daniel, Ohnemus, Annette, Ong, Li Ching, Gad, Hans Henrik, Hartmann, Rune, Lycke, Nils, Staeheli, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511795/ https://www.ncbi.nlm.nih.gov/pubmed/34659250 http://dx.doi.org/10.3389/fimmu.2021.749325

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