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Characterization of Collagen/Beta Glucan Hydrogels Crosslinked with Tannic Acid
Hydrogels based on collagen/β-glucan crosslinked with tannic acid were obtained by neutralization using dialysis. The presence of tannic acid allowed obtaining stable hydrogel materials with better mechanical properties. Tannic acid was released from matrices gradually and not rapidly. The antioxida...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512118/ https://www.ncbi.nlm.nih.gov/pubmed/34641227 http://dx.doi.org/10.3390/polym13193412 |
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author | Michalska-Sionkowska, Marta Warżyńska, Oliwia Kaczmarek-Szczepańska, Beata Łukowicz, Krzysztof Osyczka, Anna Maria Walczak, Maciej |
author_facet | Michalska-Sionkowska, Marta Warżyńska, Oliwia Kaczmarek-Szczepańska, Beata Łukowicz, Krzysztof Osyczka, Anna Maria Walczak, Maciej |
author_sort | Michalska-Sionkowska, Marta |
collection | PubMed |
description | Hydrogels based on collagen/β-glucan crosslinked with tannic acid were obtained by neutralization using dialysis. The presence of tannic acid allowed obtaining stable hydrogel materials with better mechanical properties. Tannic acid was released from matrices gradually and not rapidly. The antioxidant properties of the obtained hydrogels increased over the course of their incubation in culture media and were dependent on the concentration of tannic acid in the matrices. The obtained materials influenced dehydrogenase activity and the ATP level of pathogens. Additionally, the materials’ extracts improved the HaCaT cells’ viability. Therefore, the obtained hydrogels seem to be promising biocompatible materials which display antimicrobial properties. |
format | Online Article Text |
id | pubmed-8512118 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85121182021-10-14 Characterization of Collagen/Beta Glucan Hydrogels Crosslinked with Tannic Acid Michalska-Sionkowska, Marta Warżyńska, Oliwia Kaczmarek-Szczepańska, Beata Łukowicz, Krzysztof Osyczka, Anna Maria Walczak, Maciej Polymers (Basel) Article Hydrogels based on collagen/β-glucan crosslinked with tannic acid were obtained by neutralization using dialysis. The presence of tannic acid allowed obtaining stable hydrogel materials with better mechanical properties. Tannic acid was released from matrices gradually and not rapidly. The antioxidant properties of the obtained hydrogels increased over the course of their incubation in culture media and were dependent on the concentration of tannic acid in the matrices. The obtained materials influenced dehydrogenase activity and the ATP level of pathogens. Additionally, the materials’ extracts improved the HaCaT cells’ viability. Therefore, the obtained hydrogels seem to be promising biocompatible materials which display antimicrobial properties. MDPI 2021-10-05 /pmc/articles/PMC8512118/ /pubmed/34641227 http://dx.doi.org/10.3390/polym13193412 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Michalska-Sionkowska, Marta Warżyńska, Oliwia Kaczmarek-Szczepańska, Beata Łukowicz, Krzysztof Osyczka, Anna Maria Walczak, Maciej Characterization of Collagen/Beta Glucan Hydrogels Crosslinked with Tannic Acid |
title | Characterization of Collagen/Beta Glucan Hydrogels Crosslinked with Tannic Acid |
title_full | Characterization of Collagen/Beta Glucan Hydrogels Crosslinked with Tannic Acid |
title_fullStr | Characterization of Collagen/Beta Glucan Hydrogels Crosslinked with Tannic Acid |
title_full_unstemmed | Characterization of Collagen/Beta Glucan Hydrogels Crosslinked with Tannic Acid |
title_short | Characterization of Collagen/Beta Glucan Hydrogels Crosslinked with Tannic Acid |
title_sort | characterization of collagen/beta glucan hydrogels crosslinked with tannic acid |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512118/ https://www.ncbi.nlm.nih.gov/pubmed/34641227 http://dx.doi.org/10.3390/polym13193412 |
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