Cargando…
l-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells
The COVID-19 pandemic outbreak prompts an urgent need for efficient therapeutics, and repurposing of known drugs has been extensively used in an attempt to get to anti-SARS-CoV-2 agents in the shortest possible time. The glycoside rutin shows manifold pharmacological activities and, despite its use...
Autores principales: | Sancineto, Luca, Ostacolo, Carmine, Ortega-Alarcon, David, Jimenez-Alesanco, Ana, Ceballos-Laita, Laura, Vega, Sonia, Abian, Olga, Velazquez-Campoy, Adrian, Moretti, Silvia, Dabrowska, Agnieszka, Botwina, Pawel, Synowiec, Aleksandra, Kula-Pacurar, Anna, Pyrc, Krzysztof, Iraci, Nunzio, Santi, Claudio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512140/ https://www.ncbi.nlm.nih.gov/pubmed/34641606 http://dx.doi.org/10.3390/molecules26196062 |
Ejemplares similares
-
Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of M(pro) and Its Antiviral Activity in Cells against SARS-CoV-2
por: Mangiavacchi, Francesca, et al.
Publicado: (2021) -
Rutin Is a Low Micromolar Inhibitor of SARS-CoV-2 Main Protease 3CLpro: Implications for Drug Design of Quercetin Analogs
por: Rizzuti, Bruno, et al.
Publicado: (2021) -
Reversible rearrangement of the cellular cytoskeleton: A key to the broad-spectrum antiviral activity of novel amphiphilic polymers()
por: Dabrowska, Agnieszka, et al.
Publicado: (2023) -
Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening
por: Abian, Olga, et al.
Publicado: (2020) -
Enzyme/Nanocopper
Hybrid Nanozymes: Modulating Enzyme-like
Activity by the Protein Structure for Biosensing and Tumor Catalytic
Therapy
por: Losada-Garcia, Noelia, et al.
Publicado: (2021)