Cargando…

Esterification of Alginate with Alkyl Bromides of Different Carbon Chain Lengths via the Bimolecular Nucleophilic Substitution Reaction: Synthesis, Characterization, and Controlled Release Performance

To extend the alginate applicability for the sustained release of hydrophobic medicine in drug delivery systems, the alkyl alginate ester derivative (AAD), including hexyl alginate ester derivative (HAD), octyl alginate ester derivative (OAD), decyl alginate ester derivative (DAD), and lauryl algina...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Xiuqiong, Zhu, Qingmei, Liu, Chang, Li, Dongze, Yan, Huiqiong, Lin, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512272/ https://www.ncbi.nlm.nih.gov/pubmed/34641167 http://dx.doi.org/10.3390/polym13193351

Ejemplares similares

Theoretical Analysis on the Kinetic Isotope Effects of Bimolecular Nucleophilic Substitution (S(N)2) Reactions and Their Temperature Dependence
por: Tsai, Wan-Chen, et al.
Publicado: (2013)

Benchmark Study on the Smallest Bimolecular Nucleophilic Substitution Reaction: H(−)+CH(4) → CH(4)+H(−)
por: Swart, Marcel, et al.
Publicado: (2013)

Alkylation of Nitropyridines via Vicarious Nucleophilic Substitution
por: Antoniak, Damian, et al.
Publicado: (2022)

UDP-glucose Dehydrogenase: The First-step Oxidation Is an NAD(+)-dependent Bimolecular Nucleophilic Substitution Reaction (S(N)2)
por: Chen, Jun, et al.
Publicado: (2019)

Palladium-Catalyzed Cross Coupling of Secondary and Tertiary Alkyl Bromides with a Nitrogen Nucleophile
por: Peacock, D. Matthew, et al.
Publicado: (2016)

Interaction between DNA and Trimethyl-Ammonium Bromides with Different Alkyl Chain Lengths
por: Cheng, Chao, et al.
Publicado: (2014)

Replacing Conventional Carbon Nucleophiles with Electrophiles: Nickel-Catalyzed Reductive Alkylation of Aryl Bromides and Chlorides
por: Everson, Daniel A., et al.
Publicado: (2012)

The Molecular Structure and Self-Assembly Behavior of Reductive Amination of Oxidized Alginate Derivative for Hydrophobic Drug Delivery
por: Chen, Xiuqiong, et al.
Publicado: (2021)

Fabrication and Evaluation of Alginate/Bacterial Cellulose Nanocrystals–Chitosan–Gelatin Composite Scaffolds
por: Li, Zhengyue, et al.
Publicado: (2021)

A Study on the Correlation between the Oxidation Degree of Oxidized Sodium Alginate on Its Degradability and Gelation
por: Wang, Hongcai, et al.
Publicado: (2022)

Quaternary stereocentres via catalytic enantioconvergent nucleophilic substitution reactions of tertiary alkyl halides by alkenylmetal reagents
por: Wang, Zhaobin, et al.
Publicado: (2021)

Pd-Catalyzed Nucleophilic Fluorination of Aryl Bromides
por: Lee, Hong Geun, et al.
Publicado: (2014)

Heterolysis of Dihydrogen by Nucleophilic Calcium Alkyls
por: Wilson, Andrew S. S., et al.
Publicado: (2018)

Concerted Nucleophilic Aromatic Substitution Reactions
por: Rohrbach, Simon, et al.
Publicado: (2019)

A Study on the Direct Esterification of Monoalkylphosphates and Dialkylphosphates; The Conversion of the Latter Species to Trialkylphosphates by Alkylating Esterification †
por: Ábrányi-Balogh, Péter, et al.
Publicado: (2022)

Highly Diastereoselective Preparation of Tertiary Alkyl Isonitriles by Stereoinvertive Nucleophilic Substitution at a Nonclassical Carbocation
por: Chen, Xu, et al.
Publicado: (2023)

Palladium-catalyzed asymmetric allylic alkylation (AAA) with alkyl sulfones as nucleophiles
por: Trost, Barry M., et al.
Publicado: (2021)

Nucleophilic trifluoromethoxylation of alkyl halides without silver
por: Li, Yan, et al.
Publicado: (2020)

Alkyl Chain Length Effects of Imidazolium Ionic Liquids on Electrical and Mechanical Performances of Polyacrylamide/Alginate-Based Hydrogels
por: Chen, Chen-Kang, et al.
Publicado: (2021)

Alkyl Substituent in Heterocyclic Substrate, Carbon Skeleton Length of O-Nucleophilic Agent and Conditions Influence the Product Composition from Competitive Reactions of S(N)(ipso) Substitution by Aliphatic Oligoethers
por: Bosov, Konstantin K., et al.
Publicado: (2023)

One-Pot Synthesis of Amphiphilic Biopolymers from Oxidized Alginate and Self-Assembly as a Carrier for Sustained Release of Hydrophobic Drugs
por: Liu, Zhaowen, et al.
Publicado: (2022)

Comparative Study of Physicochemical Properties of Alginate Composite Hydrogels Prepared by the Physical Blending and Electrostatic Assembly Methods
por: Wen, Yanshi, et al.
Publicado: (2022)

General Allylic C–H Alkylation with Tertiary Nucleophiles
por: Howell, Jennifer M., et al.
Publicado: (2014)

Esterification of Aryl/Alkyl Acids Catalysed by N-bromosuccinimide under Mild Reaction Conditions
por: Čebular, Klara, et al.
Publicado: (2018)

Concerted Nucleophilic Aromatic Substitutions
por: Kwan, Eugene E., et al.
Publicado: (2018)

Nucleophilic substitution reactions of monofunctional nucleophilic reagents with cyclotriphosphazenes containing 2,2-dioxybiphenyl units
por: TANRIVERDİ EÇİK, Esra, et al.
Publicado: (2020)

Does Steric Hindrance Actually Govern the Competition between Bimolecular Substitution and Elimination Reactions?
por: Gallegos, Miguel, et al.
Publicado: (2022)

Visible light-driven Giese reaction with alkyl tosylates catalysed by nucleophilic cobalt
por: Komeyama, Kimihiro, et al.
Publicado: (2021)

Rhodium-catalyzed direct alkylation of benzylic amines using alkyl bromides
por: Anschuber, Martin, et al.
Publicado: (2018)

NHC and nucleophile chelation effects on reactive iron(ii) species in alkyl–alkyl cross-coupling
por: Fleischauer, Valerie E., et al.
Publicado: (2018)

Synthesis of Short-Chain Alkyl Butyrate through Esterification Reaction Using Immobilized Rhodococcus Cutinase and Analysis of Substrate Specificity through Molecular Docking
por: Won, Seok-Jae, et al.
Publicado: (2023)

Catalyzed Bimolecular Reactions in Responsive Nanoreactors
por: Roa, Rafael, et al.
Publicado: (2017)

Dynamic Nucleophilic Aromatic Substitution of Tetrazines
por: Santos, Tanausú, et al.
Publicado: (2021)

Nickel-catalysed cross-electrophile coupling of aryl bromides and primary alkyl bromides
por: Gao, Nanxing, et al.
Publicado: (2022)

Nucleophilic Substitution at Tetracoordinate Sulfur. Kinetics and Mechanism of the Chloride-Chloride Exchange Reaction in Arenesulfonyl Chlorides: Counterintuitive Acceleration of Substitution at Sulfonyl Sulfur by ortho-Alkyl Groups and Its Origin
por: Mikołajczyk, Marian, et al.
Publicado: (2020)

Palladium-catalyzed Heck-type reaction of secondary trifluoromethylated alkyl bromides
por: Fan, Tao, et al.
Publicado: (2017)

Two-Chamber Aminocarbonylation of Aryl Bromides and Triflates Using Amino Acids as Nucleophiles
por: Lindman, Jens, et al.
Publicado: (2023)

Ultrasound-Assisted Esterification of Valeric Acid to Alkyl Valerates Promoted by Biosilicified Lipases
por: Cebrián-García, Soledad, et al.
Publicado: (2018)

Enantioselective N-heterocyclic carbene-catalyzed nucleophilic dearomatization of alkyl pyridiniums
por: Flanigan, Darrin M., et al.
Publicado: (2017)

Unimolecular and bimolecular ion-molecule reaction dynamics
por: Baer, Thomas M, et al.
Publicado: (1994)

Cannot write session to /tmp/vufind_sessions/sess_vf2ov4b161jnmjfqe9tc644ger