Non-canonical Keap1-independent activation of Nrf2 in astrocytes by mild oxidative stress

The transcription factor Nrf2 is a stress-responsive master regulator of antioxidant, detoxification and proteostasis genes. In astrocytes, Nrf2-dependent gene expression drives cell-autonomous cytoprotection and also non-cell-autonomous protection of nearby neurons, and can ameliorate pathology in...

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Detalles Bibliográficos
Autores principales: Al-Mubarak, Bashayer R., Bell, Karen F.S., Chowdhry, Sudhir, Meakin, Paul J., Baxter, Paul S., McKay, Sean, Dando, Owen, Ashford, Michael L.J., Gazaryan, Irina, Hayes, John D., Hardingham, Giles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512624/
https://www.ncbi.nlm.nih.gov/pubmed/34626892
http://dx.doi.org/10.1016/j.redox.2021.102158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512624/
https://www.ncbi.nlm.nih.gov/pubmed/34626892
http://dx.doi.org/10.1016/j.redox.2021.102158

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