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A Uniform Benchmark for Testing SsrA-Derived Degrons in the Escherichia coli ClpXP Degradation Pathway

The ssrA degron is commonly used in fusion proteins to control protein stability in bacteria or as an interaction module. These applications often rely on the modular activities of the ssrA tag in binding to the SspB adaptor and in engaging the ClpXP protease. However, a comparison of these activiti...

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Detalles Bibliográficos
Autores principales: Klimecka, Maria Magdalena, Antosiewicz, Anna, Izert, Matylda Anna, Szybowska, Patrycja Emanuela, Twardowski, Piotr Krzysztof, Delaunay, Clara, Górna, Maria Wiktoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512704/
https://www.ncbi.nlm.nih.gov/pubmed/34641479
http://dx.doi.org/10.3390/molecules26195936