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Enantiodivergent Synthesis of Benzoquinolizidinones from L-Glutamic Acid
Benzoquinolizidinone systems were synthesized in both enantiomeric forms from L-glutamic acid. The key chiral arylethylglutarimide intermediate was synthesized from dibenzylamino-glutamate and homoveratrylamine. Aldol reaction of the glutarimide afforded a mixture of syn and anti-aldol adducts. Subs...
Autores principales: | Kuntiyong, Punlop, Namborisut, Duangkamon, Phakdeeyothin, Kunita, Chatpreecha, Rungrawin, Thammapichai, Kittisak |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512815/ https://www.ncbi.nlm.nih.gov/pubmed/34641410 http://dx.doi.org/10.3390/molecules26195866 |
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