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The effect of N-glycosylation of SARS-CoV-2 spike protein on the virus interaction with the host cell ACE2 receptor
The densely glycosylated spike (S) protein highly exposed on severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) surface mediates host cell entry by binding to the receptor angiotensin-converting enzyme 2 (ACE2). However, the role of glycosylation has not been fully understood. In this stud...
Autores principales: | Huang, Chuncui, Tan, Zeshun, Zhao, Keli, Zou, Wenjun, Wang, Hui, Gao, Huanyu, Sun, Shiwei, Bu, Dongbo, Chai, Wengang, Li, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513389/ https://www.ncbi.nlm.nih.gov/pubmed/34661088 http://dx.doi.org/10.1016/j.isci.2021.103272 |
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