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Autologous fat grafting in the face and neck: Multinational trends and knowledge of the safety, applications, and indications considering oncologic risk potential

BACKGROUND: Autologous fat grafting (AFG) is evolving in both aesthetic and reconstructive applications, since the body of evidence for its use has expanded. The earliest controversies were evident in lipofilling for oncological breast reconstruction, and to this day, some countries do not allow it...

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Autores principales: Fiedler, Lukas S, Saleh, Daniel B, Mukrowsky, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513435/
https://www.ncbi.nlm.nih.gov/pubmed/34667845
http://dx.doi.org/10.1002/lio2.649
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author Fiedler, Lukas S
Saleh, Daniel B
Mukrowsky, Alicia
author_facet Fiedler, Lukas S
Saleh, Daniel B
Mukrowsky, Alicia
author_sort Fiedler, Lukas S
collection PubMed
description BACKGROUND: Autologous fat grafting (AFG) is evolving in both aesthetic and reconstructive applications, since the body of evidence for its use has expanded. The earliest controversies were evident in lipofilling for oncological breast reconstruction, and to this day, some countries do not allow it for fear of inducing tumourigenesis in an oncologically ablated field. METHODS: We sought to review contemporary harvesting and processing techniques for AFG in the craniofacial region, therefore distributed a survey to evaluate the clinical impact of oncological risk across four European countries. RESULTS: We found no significant geographical differences between the German‐speaking and the English groups concerning their harvesting and processing technique. Half of our respondents discuss the possibility of pro‐oncologic behavior of AFG. CONCLUSION: AFG harvesting and processing techniques do not considerably vary by geography. Further studies should evaluate oncologic risk potential of AFG in head and neck tumor sites, especially because there is no excellent article regarding this phenomenon. Level of Evidence: V
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spelling pubmed-85134352021-10-18 Autologous fat grafting in the face and neck: Multinational trends and knowledge of the safety, applications, and indications considering oncologic risk potential Fiedler, Lukas S Saleh, Daniel B Mukrowsky, Alicia Laryngoscope Investig Otolaryngol Head and Neck, and Tumor Biology BACKGROUND: Autologous fat grafting (AFG) is evolving in both aesthetic and reconstructive applications, since the body of evidence for its use has expanded. The earliest controversies were evident in lipofilling for oncological breast reconstruction, and to this day, some countries do not allow it for fear of inducing tumourigenesis in an oncologically ablated field. METHODS: We sought to review contemporary harvesting and processing techniques for AFG in the craniofacial region, therefore distributed a survey to evaluate the clinical impact of oncological risk across four European countries. RESULTS: We found no significant geographical differences between the German‐speaking and the English groups concerning their harvesting and processing technique. Half of our respondents discuss the possibility of pro‐oncologic behavior of AFG. CONCLUSION: AFG harvesting and processing techniques do not considerably vary by geography. Further studies should evaluate oncologic risk potential of AFG in head and neck tumor sites, especially because there is no excellent article regarding this phenomenon. Level of Evidence: V John Wiley & Sons, Inc. 2021-09-01 /pmc/articles/PMC8513435/ /pubmed/34667845 http://dx.doi.org/10.1002/lio2.649 Text en © 2021 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals LLC on behalf of The Triological Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Head and Neck, and Tumor Biology
Fiedler, Lukas S
Saleh, Daniel B
Mukrowsky, Alicia
Autologous fat grafting in the face and neck: Multinational trends and knowledge of the safety, applications, and indications considering oncologic risk potential
title Autologous fat grafting in the face and neck: Multinational trends and knowledge of the safety, applications, and indications considering oncologic risk potential
title_full Autologous fat grafting in the face and neck: Multinational trends and knowledge of the safety, applications, and indications considering oncologic risk potential
title_fullStr Autologous fat grafting in the face and neck: Multinational trends and knowledge of the safety, applications, and indications considering oncologic risk potential
title_full_unstemmed Autologous fat grafting in the face and neck: Multinational trends and knowledge of the safety, applications, and indications considering oncologic risk potential
title_short Autologous fat grafting in the face and neck: Multinational trends and knowledge of the safety, applications, and indications considering oncologic risk potential
title_sort autologous fat grafting in the face and neck: multinational trends and knowledge of the safety, applications, and indications considering oncologic risk potential
topic Head and Neck, and Tumor Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513435/
https://www.ncbi.nlm.nih.gov/pubmed/34667845
http://dx.doi.org/10.1002/lio2.649
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