Lack of Interferon (IFN) Regulatory Factor 8 Associated with Restricted IFN-γ Response Augmented Japanese Encephalitis Virus Replication in the Mouse Brain

Interferon regulatory factor 8 (IRF8), a myeloid lineage transcription factor, emerges as an essential regulator for microglial activation. However, the precise role of IRF8 during Japanese encephalitis virus (JEV) infection in the brain remains elusive. Here, we report that JEV infection enhances I...

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Detalles Bibliográficos
Autores principales: Tripathi, Aarti, Singh Rawat, Bhupendra, Addya, Sankar, Surjit, Milan, Tailor, Prafullakumar, Vrati, Sudhanshu, Banerjee, Arup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Cellular Response to Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513486/
https://www.ncbi.nlm.nih.gov/pubmed/34379515
http://dx.doi.org/10.1128/JVI.00406-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513486/
https://www.ncbi.nlm.nih.gov/pubmed/34379515
http://dx.doi.org/10.1128/JVI.00406-21

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