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Electrodiagnostic findings in COVID-19 patients: A single center experience

OBJECTIVE: Neurological manifestations in patients with coronavirus disease 2019 (COVID-19) have been reported from early features of anosmia and dysgeusia to widespread involvement of the central nervous system, peripheral nervous system, as well as the neuromuscular junction and muscle. Our study...

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Autores principales: Hameed, Sajid, Khan, Ayisha Farooq, Khan, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Federation of Clinical Neurophysiology. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513511/
https://www.ncbi.nlm.nih.gov/pubmed/34717222
http://dx.doi.org/10.1016/j.clinph.2021.10.001
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author Hameed, Sajid
Khan, Ayisha Farooq
Khan, Sara
author_facet Hameed, Sajid
Khan, Ayisha Farooq
Khan, Sara
author_sort Hameed, Sajid
collection PubMed
description OBJECTIVE: Neurological manifestations in patients with coronavirus disease 2019 (COVID-19) have been reported from early features of anosmia and dysgeusia to widespread involvement of the central nervous system, peripheral nervous system, as well as the neuromuscular junction and muscle. Our study objective is to evaluate the electromyography and nerve conduction study (EMG/NCS) findings among COVID-19 patients and look for possible correlations. METHODS: This is a hospital-based retrospective observational study. All COVID-19 patients between the period of 1st January 2020 to 31st December 2020 undergoing an EMG/NCS were included. RESULTS: Eighteen patients (12 male and 6 female) were included. Mean age was 55 ± 12 years. 11 patients required intubation for a mean period of 18.6 days (range: 3–37 days). Electrodiagnostic findings were consistent with a myopathy in a majority of these patients (82%). Five of them also had a concurrent axonal neuropathy. In the remaining patients who did not require intubation (n = 7), three patients had myopathic EMG changes and one had Guillain Barre syndrome. CONCLUSION: At this time, there are no neuromuscular-specific recommendations for patients who contract COVID-19. Only time and additional data will unveil the varying nature and potential neurological sequelae of COVID-19. SIGNIFICANCE: Myopathic EMG changes are commonly seen in critically ill COVID-19 patients, especially with a prolonged hospital stay.
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spelling pubmed-85135112021-10-13 Electrodiagnostic findings in COVID-19 patients: A single center experience Hameed, Sajid Khan, Ayisha Farooq Khan, Sara Clin Neurophysiol Article OBJECTIVE: Neurological manifestations in patients with coronavirus disease 2019 (COVID-19) have been reported from early features of anosmia and dysgeusia to widespread involvement of the central nervous system, peripheral nervous system, as well as the neuromuscular junction and muscle. Our study objective is to evaluate the electromyography and nerve conduction study (EMG/NCS) findings among COVID-19 patients and look for possible correlations. METHODS: This is a hospital-based retrospective observational study. All COVID-19 patients between the period of 1st January 2020 to 31st December 2020 undergoing an EMG/NCS were included. RESULTS: Eighteen patients (12 male and 6 female) were included. Mean age was 55 ± 12 years. 11 patients required intubation for a mean period of 18.6 days (range: 3–37 days). Electrodiagnostic findings were consistent with a myopathy in a majority of these patients (82%). Five of them also had a concurrent axonal neuropathy. In the remaining patients who did not require intubation (n = 7), three patients had myopathic EMG changes and one had Guillain Barre syndrome. CONCLUSION: At this time, there are no neuromuscular-specific recommendations for patients who contract COVID-19. Only time and additional data will unveil the varying nature and potential neurological sequelae of COVID-19. SIGNIFICANCE: Myopathic EMG changes are commonly seen in critically ill COVID-19 patients, especially with a prolonged hospital stay. International Federation of Clinical Neurophysiology. Published by Elsevier B.V. 2021-12 2021-10-13 /pmc/articles/PMC8513511/ /pubmed/34717222 http://dx.doi.org/10.1016/j.clinph.2021.10.001 Text en © 2021 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Hameed, Sajid
Khan, Ayisha Farooq
Khan, Sara
Electrodiagnostic findings in COVID-19 patients: A single center experience
title Electrodiagnostic findings in COVID-19 patients: A single center experience
title_full Electrodiagnostic findings in COVID-19 patients: A single center experience
title_fullStr Electrodiagnostic findings in COVID-19 patients: A single center experience
title_full_unstemmed Electrodiagnostic findings in COVID-19 patients: A single center experience
title_short Electrodiagnostic findings in COVID-19 patients: A single center experience
title_sort electrodiagnostic findings in covid-19 patients: a single center experience
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513511/
https://www.ncbi.nlm.nih.gov/pubmed/34717222
http://dx.doi.org/10.1016/j.clinph.2021.10.001
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