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A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic aetiology with obesity

BACKGROUND: Lung function is a heritable complex phenotype with obesity being one of its important risk factors. However, knowledge of their shared genetic basis is limited. Most genome-wide association studies (GWASs) for lung function have been based on European populations, limiting the generalis...

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Detalles Bibliográficos
Autores principales: Zhu, Zhaozhong, Li, Jiachen, Si, Jiahui, Ma, Baoshan, Shi, Huwenbo, Lv, Jun, Cao, Weihua, Guo, Yu, Millwood, Iona Y., Walters, Robin G., Lin, Kuang, Yang, Ling, Chen, Yiping, Du, Huaidong, Yu, Bo, Hasegawa, Kohei, Camargo, Carlos A., Moffatt, Miriam F., Cookson, William O.C., Chen, Junshi, Chen, Zhengming, Li, Liming, Yu, Canqing, Liang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513692/
https://www.ncbi.nlm.nih.gov/pubmed/33766948
http://dx.doi.org/10.1183/13993003.00199-2021