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Restoring the Molecular Clockwork within the Suprachiasmatic Hypothalamus of an Otherwise Clockless Mouse Enables Circadian Phasing and Stabilization of Sleep-Wake Cycles and Reverses Memory Deficits
The timing and quality of sleep-wake cycles are regulated by interacting circadian and homeostatic mechanisms. Although the suprachiasmatic nucleus (SCN) is the principal clock, circadian clocks are active across the brain and the respective sleep-regulatory roles of SCN and local clocks are unclear...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Society for Neuroscience
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513698/ https://www.ncbi.nlm.nih.gov/pubmed/34446572 http://dx.doi.org/10.1523/JNEUROSCI.3141-20.2021 |