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Restoring the Molecular Clockwork within the Suprachiasmatic Hypothalamus of an Otherwise Clockless Mouse Enables Circadian Phasing and Stabilization of Sleep-Wake Cycles and Reverses Memory Deficits

The timing and quality of sleep-wake cycles are regulated by interacting circadian and homeostatic mechanisms. Although the suprachiasmatic nucleus (SCN) is the principal clock, circadian clocks are active across the brain and the respective sleep-regulatory roles of SCN and local clocks are unclear...

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Detalles Bibliográficos
Autores principales: Maywood, Elizabeth S., Chesham, Johanna E., Winsky-Sommerer, Raphaelle, Hastings, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513698/
https://www.ncbi.nlm.nih.gov/pubmed/34446572
http://dx.doi.org/10.1523/JNEUROSCI.3141-20.2021

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